Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29684657 | 0.93 | TSHR (0.53) | TSHRALDH1A1CYP2C9KDM4EGAA | |
| SCHEMBL28231556 | 0.92 | TSHR (0.56) | TSHRALDH1A1CYP2C9KDM4EGAA | |
| SCHEMBL1726734 | 0.90 | TSHR (0.58) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL1819502 | 0.88 | TSHR (0.49) | TSHRALDH1A1CYP2C9KDM4EGAA | |
| Oxalic Acid SCHEMBL29685154 | 0.86 | TSHR (0.55) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL29684863 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL2435688 | 0.80 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL28263344 | 0.76 | TSHR (0.51) | TSHRALDH1A1CYP2C9KDM4EGLA | |
| Gluconic Acid SCHEMBL29684835 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4EGAAGLA | |
| SCHEMBL16713682 | 0.74 | CYP2C9 (0.42) | TSHRALDH1A1CYP2C9KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162177-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | PHARMATROPHIX, INC. | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162177-A1 | CRYSTALLINE FORMS OF NEUROTROPHIN MIMETIC COMPOUNDS AND THEIR SALTS | BDNF, NGF, NTRK2 | TSHR 971/4885ALDH1A1 4364/4885CYP2C9 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.