Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PLEC | Q15149 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19366237 | 0.79 | L3MBTL1 (0.49) | ALDH1A1APAF1L3MBTL1HTTNPSR1 | |
| SCHEMBL10408681 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPSR1SMN1; SMN2LMNASOAT1 | |
| SCHEMBL10408702 | 0.73 | L3MBTL1 (0.46) | L3MBTL1NPSR1SMN1; SMN2LMNASOAT1 | |
| SCHEMBL28016716 | 0.71 | SOAT1 (0.51) | SMN1; SMN2SOAT1 | |
| SCHEMBL9971709 | 0.70 | TLR8 (0.35) | ALDH1A1APAF1L3MBTL1TLR8SOAT1 | |
| SCHEMBL2241352 | 0.70 | TLR8 (0.35) | ALDH1A1APAF1L3MBTL1TLR8SOAT1 | |
| SCHEMBL309485 | 0.70 | TLR8 (0.53) | ALDH1A1APAF1L3MBTL1HTTNPSR1 | |
| SCHEMBL6291460 | 0.70 | MEN1 (0.64) | ALDH1A1APAF1KMT2AMEN1L3MBTL1 | |
| SCHEMBL17921774 | 0.69 | L3MBTL1 (0.52) | KMT2AL3MBTL1HTTLMNAPOLB | |
| SCHEMBL10330191 | 0.69 | MEN1 (0.40) | ALDH1A1APAF1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315788-A2 | METAL-LIGAND COMPLEXES AND CATALYSTS | Dow Global Technologies LLC (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010022228-A2 | METAL-LIGAND COMPLEXES AND CATALYSTS | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2010-02-25 | — | — | WO | disclosed |