SCHEMBL19366237

SCHEMBL19366237

CCCCNc1ccccc1C(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.49
TLR8 Q9NR97 1/20 0.44
APAF1 O14727 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
POLB P06746 2/20 0.41
UTS2R Q9UKP6 1/20 0.40
NLRP3 Q96P20 1/20 0.40
SOAT1 P35610 1/20 0.40
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
KDM4E B2RXH2 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ACP1 P24666 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10408702 0.93 L3MBTL1 (0.46) L3MBTL1SOAT1NPSR1SMN1; SMN2
SCHEMBL10408681 0.93 L3MBTL1 (0.46) L3MBTL1SOAT1NPSR1SMN1; SMN2
SCHEMBL17921774 0.89 L3MBTL1 (0.52) L3MBTL1POLBNLRP3MAPTHTT
SCHEMBL309485 0.82 TLR8 (0.53) L3MBTL1TLR8APAF1ALDH1A1CYP1A2
SCHEMBL2698261 0.80 L3MBTL1 (0.50) L3MBTL1CYP1A2CYP3A4POLBNLRP3
SCHEMBL28016716 0.79 SOAT1 (0.51) SOAT1SMN1; SMN2
SCHEMBL17920550 0.79 L3MBTL1 (0.50) L3MBTL1ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL12828379 0.79 L3MBTL1 (0.50) L3MBTL1ALDH1A1POLBNLRP3MAPT
SCHEMBL2241352 0.79 TLR8 (0.35) L3MBTL1TLR8APAF1ALDH1A1CYP1A2
SCHEMBL1819611 0.79 ALDH1A1 (0.40) L3MBTL1TLR8APAF1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-17 US disclosed
EP-3429355-B1 SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS BAYER CROPSCIENCE AG (DE) 2020-02-05 EP disclosed
CN-108779298-A RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, AND RUBBER PRODUCT 株式会社普利司通 2018-11-09 CN disclosed
CN-108350129-A Multiple copolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2018-07-31 CN disclosed
CN-108290972-A The manufacturing method of polymerization catalyst composition and conjugated diene polymer 株式会社普利司通 2018-07-17 CN disclosed
CN-108137757-A Multiple copolymer, rubber composition, crosslinked rubber composition, rubber and tire 株式会社普利司通 2018-06-08 CN disclosed
CN-108137759-A Multiple copolymer, rubber composition, crosslinked rubber composition and rubber 株式会社普利司通 2018-06-08 CN disclosed
CN-108137758-A Multiple copolymer, rubber composition, crosslinked rubber composition and rubber 株式会社普利司通 2018-06-08 CN disclosed
CN-108137767-A Multipolymer, rubber composition, crosslinked rubber composition and rubber product 株式会社普利司通 2018-06-08 CN disclosed
CN-108137745-A Multiple copolymer, rubber composition, crosslinked rubber composition and rubber 株式会社普利司通 2018-06-08 CN disclosed
CN-103403081-A Rubber composition, rubber composition for tire sidewall, crosslinked rubber composition, and tire BRIDGESTONE CORP 2013-11-20 CN disclosed
CN-103154058-A Copolymer of conjugated diene compound and non-conjugated olefin, rubber composition, and tire BRIDGESTONE CORP 2013-06-12 CN disclosed
CN-103154061-A Copolymer, rubber composition, cross-linked rubber composition, and tire BRIDGESTONE CORP 2013-06-12 CN disclosed
CN-103154045-A Copolymer and manufacturing method for same BRIDGESTONE CORP 2013-06-12 CN disclosed
CN-103154059-A Copolymer of conjugated diene compound and non-conjugated olefin, rubber composition, crosslinked rubber composition, and tire BRIDGESTONE CORP 2013-06-12 CN disclosed
CN-103140515-A Copolymer, rubber composition, cross-linked rubber composition, and tire BRIDGESTONE CORP (JP) 2013-06-05 CN disclosed
CN-103140521-A Method for controlling chain structure in copolymers BRIDGESTONE CORP 2013-06-05 CN disclosed
CN-103140516-A Copolymer of conjugated diene compound and non-conjugated olefin, rubber composition, crosslinked rubber composition, and tire BRIDGESTONE CORP 2013-06-05 CN disclosed
CN-102112508-A Aromatic vinyl compound-conjugated diene compound copolymer, method for producing the same, rubber composition and tire BRIDGESTONE CORP 2011-06-29 CN disclosed
CN-101796084-A Polybutadiene, and rubber composition and tire using same BRIDGESTONE CORP 2010-08-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200288710-A1 SUBSTITUTED SULPHONAMIDES FOR CONTROLLING ANIMAL PESTS DDT, MPST, STOM L3MBTL1 288/4885TLR8 3873/4885APAF1 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.