Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164791 | 0.84 | THRB (0.48) | THRBTSHRALDH1A1PPARDHSD17B10 | |
| SCHEMBL18196369 | 0.82 | THRB (0.39) | THRBTSHRALDH1A1PPARDCA12 | |
| SCHEMBL8517689 | 0.81 | THRB (0.48) | THRBTSHRALDH1A1HSD17B10 | |
| SCHEMBL13266973 | 0.77 | TSHR (0.41) | TSHRALDH1A1PPARDCA12CA1 | |
| SCHEMBL14955789 | 0.76 | THRB (0.44) | THRBTSHRALDH1A1PPARDHSD17B10 | |
| SCHEMBL23746701 | 0.73 | ALDH1A1 (0.50) | THRBTSHRALDH1A1 | |
| SCHEMBL31454007 | 0.73 | TSHR (0.56) | THRBTSHRALDH1A1PPARDHSD17B10 | |
| SCHEMBL17449489 | 0.72 | TSHR (0.46) | THRBTSHRALDH1A1PPARD | |
| SCHEMBL55860 | 0.71 | TSHR (0.40) | THRBTSHRALDH1A1 | |
| SCHEMBL14955865 | 0.71 | TSHR (0.49) | THRBTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176386-A1 | ARCHITECTURAL COATINGS CONTAINING FLUORINATED POLYMERIC ADDITIVES | THE CHEMOURS COMPANY TT, LLC (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016176264-A1 | FLUORINATED AMINE COMPLEX ADDITIVES FOR ARCHITECTURAL COATINGS | THE CHEMOURS COMPANY TT, LLC (US) | 2016-11-03 | — | — | WO | disclosed |