SCHEMBL8517689

SCHEMBL8517689

C=C(C)C(=O)OCNC(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 5/20 0.43
ALDH1A1 P00352 6/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
EGLN1 Q9GZT9 1/20 0.36
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GLA P06280 1/20 0.35
KMT2A Q03164 1/20 0.35
GLO1 Q04760 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23746701 0.84 ALDH1A1 (0.50) THRBTSHRALDH1A1MGAMGAA
SCHEMBL55860 0.81 TSHR (0.40) THRBTSHRALDH1A1
SCHEMBL4087391 0.81 THRB (0.55) THRBTSHRALDH1A1MGAMGAA
SCHEMBL22217175 0.81 TSHR (0.42) THRBTSHRALDH1A1
SCHEMBL18196370 0.81 THRB (0.39) THRBTSHRALDH1A1HSD17B10
SCHEMBL14195923 0.79 ALDH1A1 (0.56) TSHRALDH1A1MGAMGAASI
SCHEMBL822676 0.79 TSHR (0.48) THRBTSHRALDH1A1MGAMGAA
SCHEMBL8928140 0.79 TSHR (0.54) THRBTSHRACHE
SCHEMBL19409375 0.79 THRB (0.64) THRBTSHRALDH1A1MGAMGAA
SCHEMBL15030 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0488374-B1 Epoxy resin compositions and cured products thereof SHINETSU CHEMICAL CO (JP) 1999-04-07 EP claimed
US-5225484-A With thermoplastic SHIN-ETSU CHEMICAL CO., LTD (JP) 1993-07-06 US claimed
EP-0488374-A2 Epoxy resin compositions and cured products thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-06-03 EP claimed
CN-117417488-A Acrylic acid modified waterborne polyurethane dispersoid and preparation method and application thereof 广东花果山环保科技有限公司 2024-01-19 CN disclosed
CN-211684340-U Paste formula used repeatedly doodle board 浙江道明光电科技有限公司 2020-10-16 CN disclosed
CN-104193947-B Flame-retarded heat-conducting compound polyurethane material and preparation method thereof 华南理工大学 2016-10-05 CN disclosed
CN-105949878-A Preparation method of water-based ink 周荣 2016-09-21 CN disclosed
CN-104193947-A Flame retardant heat conducting polyurethane composite material and preparation method thereof UNIV SOUTH CHINA TECH 2014-12-10 CN disclosed
EP-0488374-B1 Epoxy resin compositions and cured products thereof SHINETSU CHEMICAL CO (JP) 1999-04-07 EP disclosed
US-5643975-A SEMICONDUCTORS FORMED BY ENCAPSULATION WITH EPOXY RESIN-PHENOLIC RESIN MIXTURES SHIN-ETSU CHEMICAL COMPANY, LIMITED (JP) 1997-07-01 US disclosed
US-5225484-A With thermoplastic SHIN-ETSU CHEMICAL CO., LTD (JP) 1993-07-06 US disclosed
EP-0488374-A2 Epoxy resin compositions and cured products thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-06-03 EP disclosed
US-4780512-A Polyurethane acrylate compositions TYNDALE PLAINS-HUNTER LTD. (US) 1988-10-25 US disclosed