Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16614406 | 0.83 | ATM (0.39) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL14812118 | 0.77 | ATM (0.35) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL30233576 | 0.75 | ALOX15 (0.42) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL25024421 | 0.75 | ALOX15 (0.42) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL25025784 | 0.75 | ALOX15 (0.42) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL18214762 | 0.74 | ATM (0.42) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL6604915 | 0.71 | ATM (0.39) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL25804455 | 0.71 | ATM (0.39) | ATMALDH1A1KDM4EALOX15MTNR1A | |
| SCHEMBL77511 | 0.71 | RECQL (0.55) | ATMALDH1A1KDM4E | |
| SCHEMBL9620230 | 0.71 | ATM (0.39) | ATMALDH1A1KDM4EALOX15MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318862-A1 | SYNTHESIS OF DELTA 12-PGJ3 AND RELATED COMPOUNDS | DGKZ, DGKG, DNAJA3 | ATM 2254/4885ALDH1A1 3849/4885KDM4E 3528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.