Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18196906 | 0.85 | HTR1A (0.38) | HTR1AEPHX2BCHEACHEADRB2 | |
| SCHEMBL15013195 | 0.78 | KDM4E (0.44) | HTR1AEPHX2ADRB2ADRB1KDM4E | |
| SCHEMBL1779571 | 0.78 | EPHX1 (0.58) | EPHX1EPHX2NPC1RAB9AALDH1A1 | |
| SCHEMBL18190630 | 0.76 | HTR1A (0.41) | HTR1AEPHX2NPC1RAB9AADRB2 | |
| SCHEMBL18190570 | 0.69 | HTR1A (0.41) | HTR1ANPC1RAB9AADRB2ADRB1 | |
| SCHEMBL3362927 | 0.68 | EPHX2 (0.63) | EPHX1EPHX2NPC1RAB9AALDH1A1 | |
| SCHEMBL3188537 | 0.67 | GRIN2D (0.50) | EPHX1EPHX2 | |
| SCHEMBL27647894 | 0.66 | P2RX7 (0.36) | EPHX2 | |
| SCHEMBL7003873 | 0.65 | GPR84 (0.41) | — | |
| SCHEMBL19914464 | 0.65 | MEN1 (0.47) | HTR1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |