SCHEMBL18196919

SCHEMBL18196919

CNCc1cn(S(=O)(=O)c2cccc(F)c2)c(-c2c(F)cccc2F)c1OC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ HTR6 P50406 10/20 0.40
▸ MAPT P10636 1/20 0.38
▸ DRD2 P14416 1/20 0.37
▸ KAT6A Q92794 1/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ GFER P55789 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ POLB P06746 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ HTR2A P28223 2/20 0.35
▸ HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL20530215 0.99 HTR6 (0.39) HTR6MAPTDRD2KAT6AKMT2A
SCHEMBL18196882 0.95 HTR6 (0.39) HTR6MAPTDRD2KAT6AKMT2A
Hydrochloric Acid SCHEMBL20530218 0.94 HTR6 (0.39) HTR6MAPTDRD2KAT6AKMT2A
SCHEMBL18196933 0.93 HTR6 (0.37) HTR6MAPTDRD2KAT6AKMT2A
SCHEMBL18196923 0.93 HTR6 (0.38) HTR6MAPTDRD2KAT6AKMT2A
Hydrochloric Acid SCHEMBL20530207 0.92 HTR6 (0.36) HTR6MAPTDRD2KAT6AKMT2A
Hydrochloric Acid SCHEMBL20530216 0.92 HTR6 (0.38) HTR6MAPTDRD2KAT6AKMT2A
SCHEMBL18190930 0.91 LMNA (0.43) HTR6MAPTDRD2KAT6A
SCHEMBL18196943 0.91 KAT6A (0.40) HTR6MAPTKAT6AKMT2APOLB
SCHEMBL18190928 0.90 HTR6 (0.43) HTR6KAT6AKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197867-B1 NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAE WOONG PHARMA (KR) 2018-11-14 — — EP claimed
US-10100010-B1 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2018-10-16 — — US claimed
EP-3197867-B1 NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAE WOONG PHARMA (KR) 2018-11-14 — — EP disclosed
US-10100010-B1 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2018-10-16 — — US disclosed
WO-2016175555-A2 NOVEL 4-METHOXY PYRROLE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2016-11-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10100010-B1 4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same GIPR, GRPR, HTR3E HTR6 38/4885MAPT 4169/4885DRD2 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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