SCHEMBL1592533

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1592361	0.91	XPO1 (0.67)	XPO1PARP1MEN1KMT2AL3MBTL1
	SCHEMBL1592549	0.87	XPO1 (0.56)	XPO1PARP1L3MBTL1GAAMAPT
	SCHEMBL1592535	0.85	XPO1 (0.41)	XPO1ELANEPARP1TNKSTNKS2
	SCHEMBL1592387	0.83	XPO1 (0.53)	XPO1MEN1KMT2AL3MBTL1KDM4E
	SCHEMBL23872058	0.77	TNKS (0.48)	XPO1PARP1TNKSTNKS2MEN1
	SCHEMBL23872048	0.76	XPO1 (0.52)	XPO1MEN1KMT2AKDM4EGAA
	SCHEMBL1592575	0.75	LMNA (0.51)	XPO1ELANEMEN1KMT2AKDM4E
	SCHEMBL1592523	0.74	XPO1 (1.00)	XPO1PARP1
	SCHEMBL1592364	0.74	XPO1 (0.46)	XPO1PARP1TNKSTNKS2MEN1
	SCHEMBL1592940	0.74	XPO1 (0.46)	XPO1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.