Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATP4A | P20648 | 13/20 | 0.45 |
| ▸ | ATP4B | P51164 | 13/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197976 | 0.84 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL5879530 | 0.80 | CYP1A2 (0.50) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL16386285 | 0.79 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10776417 | 0.79 | SLC22A2 (0.50) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8708729 | 0.79 | CYP1A2 (0.49) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL18346920 | 0.77 | HRH2 (0.56) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| Bromide SCHEMBL8707683 | 0.77 | CYP1A2 (0.48) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8934520 | 0.77 | SLC22A2 (0.49) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL11214613 | 0.76 | HRH2 (0.57) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL22296554 | 0.75 | HRH2 (0.53) | CYP2D6CYP1A2CYP2C9CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-9745274-B2 | Compound, organic cation transporter 3 detection agent, and organic cation transporter 3 activity inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SHIN NIPPON BIOMEDICAL LABORATORIES, LTD. (JP) | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318886-A1 | Novel Compound, Organic Cation Transporter 3 Detection Agent, And Organic Cation Transporter 3 Activity Inhibitor | SLCO1B3, SLC22A8, SLC10A6 | CYP2D6 505/4885CYP1A2 1012/4885CYP2C9 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.