Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | KIF11 | P52732 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948882 | 0.89 | KMT2A (0.48) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL23040384 | 0.83 | KIF11 (0.45) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL10002173 | 0.83 | KIF11 (0.45) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL29377581 | 0.81 | ALDH1A1 (0.64) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL256203 | 0.81 | ALDH1A1 (0.64) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL12772920 | 0.81 | TDP1 (0.93) | KMT2AMEN1TDP1ALDH1A1TP53 | |
| SCHEMBL10002175 | 0.80 | DHODH (0.43) | KMT2AMEN1TDP1KIF11NPC1 | |
| Hydrochloric Acid SCHEMBL8878556 | 0.79 | ALDH1A1 (0.61) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL5715974 | 0.79 | NPC1 (0.47) | KMT2AMEN1TDP1KIF11NPC1 | |
| SCHEMBL3903661 | 0.78 | KIF11 (0.61) | KMT2AMEN1TDP1KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016174813-A1 | 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING HETEROMONOCYCLIC GROUPS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY DEVICE CONTAINING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2016-11-03 | — | — | WO | disclosed |