Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002173 | 0.96 | KIF11 (0.45) | DHODHKIF11NPC1RAB9AKMT2A | |
| SCHEMBL24495643 | 0.81 | MAPT (0.52) | KIF11KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL18199870 | 0.80 | KMT2A (0.61) | KIF11NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL297275 | 0.80 | ALDH1A1 (0.59) | KIF11NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL4322427 | 0.79 | KIF11 (0.61) | DHODHKIF11NPC1RAB9AKMT2A | |
| SCHEMBL23319641 | 0.79 | KIF11 (0.61) | DHODHKIF11NPC1RAB9AKMT2A | |
| SCHEMBL25515089 | 0.78 | KIF11 (0.50) | DHODHKIF11NPC1RAB9AKMT2A | |
| SCHEMBL23040384 | 0.77 | KIF11 (0.45) | KIF11NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL19585564 | 0.73 | DHODH (0.56) | DHODHKIF11KMT2AALDH1A1MEN1 | |
| SCHEMBL14666784 | 0.73 | AKR1C2 (0.49) | DHODHKIF11NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016146-A1 | POROUS CRYSTAL COMPRISING AMMONIA BORANE AND A PRODUCTION METHOD THEREFOR | INSILICOTECH CO., LTD (KR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016146-A1 | POROUS CRYSTAL COMPRISING AMMONIA BORANE AND A PRODUCTION METHOD THEREFOR | FAR1, GOT1, WEE1 | DHODH 2192/4885KIF11 1384/4885NPC1 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.