⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682287 | 0.81 | CES2 (0.39) | — | |
| SCHEMBL568600 | 0.79 | — | — | |
| SCHEMBL1674356 | 0.77 | — | — | |
| SCHEMBL2181763 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL9626058 | 0.77 | DAO (0.54) | — | |
| SCHEMBL1750114 | 0.77 | HDAC8 (0.45) | — | |
| SCHEMBL25819048 | 0.77 | GSK3B (0.40) | — | |
| SCHEMBL365156 | 0.77 | CA1 (0.45) | — | |
| SCHEMBL3094449 | 0.76 | — | — | |
| SCHEMBL3094452 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260138956-A1 | NOVEL COMPOUNDS AND USES THEREOF | RECURSION PHARMACEUTICALS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12552757-B2 | NRF2-activating compound | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2026-02-17 | — | — | US | disclosed |
| US-20240132519-A1 | NRF2-ACTIVATING COMPOUND | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2024-04-25 | — | — | US | disclosed |
| EP-4273145-A1 | NRF2-ACTIVATING COMPOUND | Senju Pharmaceutical Co., Ltd. (JP) | 2023-11-08 | — | — | EP | disclosed |
| EP-4273145-A1 | NRF2-ACTIVATING COMPOUND | Senju Pharmaceutical Co., Ltd. (JP) | 2023-11-08 | — | — | EP | disclosed |
| US-11807644-B2 | Methods and compounds for restoring mutant p53 function | PMV PHARMACEUTICALS, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| CN-116669744-A | Nrf2 activating compounds | 千寿制药株式会社 | 2023-08-29 | — | — | CN | disclosed |
| US-20230024995-A1 | NRF2-ACTIVATING COMPOUND | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20230024995-A1 | NRF2-ACTIVATING COMPOUND | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20220396581-A1 | COMPOUNDS FOR THE TREATMENT OF PARAMYXOVIRUS VIRAL INFECTIONS | Janssen Biopharma, Inc. (US) | 2022-12-15 | — | — | US | disclosed |
| EP-0610032-A1 | Acetanilide derivatives | ZENECA LIMITED (GB) | 1994-08-10 | — | — | EP | disclosed |
| US-5332757-A | Enzyme inhibitors | ZENECA LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| EP-0316179-B1 | Photochromic compounds | TOKUYAMA SODA KK (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0555068-A1 | Oxime derivatives as 5-lipoxygenase inhibitors | ZENECA LIMITED (GB) | 1993-08-11 | — | — | EP | disclosed |
| US-4960678-A | FULGIDES, FULGIMIDES AND HIGH MOLECULAR POLYMER; LENSES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0140540-B1 | PHOTOCHROMIC COMPOUNDS AND THEIR USES IN PHOTOREACTIVE LENSES | THE PLESSEY COMPANY plc (GB) | 1990-05-09 | — | — | EP | disclosed |
| US-4882438-A | DURABILITY; HETEROCYCLIC IMIDE COMPOUND | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0316179-A2 | Photochromic compounds | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |
| US-4685783-A | Polychromic tetracyclo-spiro-adamatylidene derivatives, and polychromic lens incorporating said compounds | THE PLESSEY COMPANY P.L.C. (GB) | 1987-08-11 | — | — | US | disclosed |
| EP-0140540-A2 | Photochromic compounds and their uses in photoreactive lenses | THE PLESSEY COMPANY plc (GB) | 1985-05-08 | — | — | EP | disclosed |