⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9626058 | 0.98 | DAO (0.54) | — | |
| SCHEMBL5155506 | 0.85 | DAO (0.66) | — | |
| SCHEMBL8711639 | 0.84 | DAO (0.42) | — | |
| SCHEMBL27682287 | 0.83 | CES2 (0.39) | — | |
| SCHEMBL1674356 | 0.79 | — | — | |
| SCHEMBL2181763 | 0.79 | — | — | |
| SCHEMBL1820040 | 0.79 | — | — | |
| SCHEMBL9929411 | 0.75 | DAO (0.60) | — | |
| SCHEMBL2225273 | 0.74 | HDAC6 (0.42) | — | |
| SCHEMBL365156 | 0.74 | CA1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512031-B | Preparation method of LSD1enzyme inhibitor TAK-418 intermediate compound | 都创(上海)医药开发有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-108350034-B | Antimicrobial polymyxin derived compounds | 莫纳什大学 | 2022-03-11 | — | — | CN | claimed |
| CN-113512031-A | Preparation method of LSD1enzyme inhibitor TAK-418 intermediate compound | 都创(上海)医药开发有限公司 | 2021-10-19 | — | — | CN | claimed |
| EP-0186252-B1 | USE OF THIOPHENE COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT AGAINST TUMOURS | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1992-04-01 | — | — | EP | claimed |
| CN-119707952-B | Thiadiazolidinone derivative with PTPN2/PTPN1 inhibitory activity, and preparation method and application thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| US-12622891-B2 | AMP-activated protein kinase activator | KYOTO PHARMACEUTICAL UNIVERSITY (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12624023-B2 | Sulfonylurea derivatives and uses thereof | NodThera Limited (GB) | 2026-05-12 | — | — | US | disclosed |
| US-12577245-B2 | Sulfonyl benzamide derivatives as Bcl-2 inhibitors | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2026-03-17 | — | — | US | disclosed |
| EP-3983407-B1 | SULFONYLUREA DERIVATIVES AND USES THEREOF | NODTHERA LTD (GB) | 2025-11-12 | — | — | EP | disclosed |
| US-12454525-B2 | IL4I1 inhibitors and methods of use | MERCK SHARP & DOHME LLC (US) | 2025-10-28 | — | — | US | disclosed |
| US-20250179055-A1 | Substituted 2-(pyrrolidine-3-yl)acetic acid derivative, preparation method and use thereof | INNOVSTONE THERAPEUTICS LIMITED (CN) | 2025-06-05 | — | — | US | disclosed |
| WO-2025103442-A1 | SUBSTITUTED 2-(PYRROLIDIN-3-YL)ACETIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2025-05-22 | — | — | WO | disclosed |
| EP-0393936-A1 | 3-substituted-2-oxindole derivatives as antiinflammatory agents | PFIZER INC. (US) | 1990-10-24 | — | — | EP | disclosed |
| CN-1038098-A | The preparation method of new glutamic acid derivatives | UNIV PRINCETON (US) | 1989-12-20 | — | — | CN | disclosed |
| EP-0343801-A2 | N-(5,6,7,8-tetrahydropyrido(2,3-D)pyrimidin-6-yl-alkanoyl)-glutamic acid derivatives | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-29 | — | — | EP | disclosed |
| US-4882334-A | ANTITUMOR AGENTS INHIBIT ENZYMES WHICH USE FOLIC ACID OR ITS METABOLITES AS SUBSTRATE; ANTICARCINOGENIC | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-11-21 | — | — | US | disclosed |
| US-4767758-A | RADIOSENSITIZING CELLS; BLOCKING REACTION OF OXYGEN RADICALS | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1988-08-30 | — | — | US | disclosed |
| EP-0186252-A2 | Use of thiophene compounds for the manufacture of a medicament against tumours | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1986-07-02 | — | — | EP | disclosed |
| US-4282246-A | Antidiabetic furancarboxylic and thiphenecarboxylic acids | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4123550-A | Bicyclo[3.1.0]hexylethylaminocarbonyl-substituted heteroaryl cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1978-10-31 | — | — | US | disclosed |