Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550521 | 0.85 | POLB (0.52) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL2093314 | 0.84 | TSHR (0.47) | POLBALDH1A1GAAMAPTTSHR | |
| SCHEMBL2097563 | 0.83 | GPBAR1 (0.47) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL30936965 | 0.83 | GPBAR1 (0.47) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL6393802 | 0.83 | FSCN1 (0.61) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL28867961 | 0.82 | GPBAR1 (0.50) | POLBGPBAR1PIK3CAPIK3CBKDM4E | |
| SCHEMBL2089203 | 0.82 | MEN1 (0.46) | POLBGPBAR1ALDH1A1GAAKDM4E | |
| SCHEMBL7831273 | 0.82 | GPBAR1 (0.46) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL10945996 | 0.82 | GPBAR1 (0.46) | POLBGPBAR1ALDH1A1FSCN1PIK3CA | |
| SCHEMBL1624396 | 0.80 | GPBAR1 (0.44) | POLBGPBAR1ALDH1A1FSCN1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730996-A | Intercalates and expoliates formed with organic pesticide compounds and compositions containing the same | AMCOL INTERNATIONAL CORPORATION (US) | 1998-03-24 | — | — | US | claimed |
| US-4315017-A | Triazole derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1982-02-09 | — | — | US | claimed |
| US-4086246-A | REACTION OF PHOSGENE WITH A PHENOL AND PRIMARY AMINE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA (HU) | 1978-04-25 | — | — | US | claimed |
| EP-3536720-B1 | MODIFIED CONJUGATED DIENE-BASED POLYMER AND RUBBER COMPOSITION COMPRISING SAME | LG CHEMICAL LTD (KR) | 2022-01-05 | — | — | EP | disclosed |
| EP-3925985-A1 | MODIFIED CONJUGATED DIENE-BASED POLYMER | LG CHEM, LTD. (KR) | 2021-12-22 | — | — | EP | disclosed |
| US-20210352892-A1 | MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2021-11-18 | — | — | US | disclosed |
| WO-2020210750-A1 | MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2020-10-15 | — | — | WO | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-7947712-B2 | Antiarthritic agents; asthma; chronic obstructive pulminary diosrders; atherosclerosis; vision defects; hepatitis; central nervous system disorders; cardiovascular disorders; wound healing agents; restenosis; cirrhosis; multiple sclerosis; glomerulonephritis; graft versus host disease; antidiabetic agent | WYETH LLC (US) | 2011-05-24 | — | — | US | disclosed |
| US-20080269213-A1 | 8-Hydroxyquinoline compounds and methods thereof | WYETH (US) | 2008-10-30 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-3956306-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3941829-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
| US-3940412-A | 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them | CIBA-GEIGY AG (CH) | 1976-02-24 | — | — | US | disclosed |
| US-3935224-A | 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
| US-3933945-A | O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3934010-A | MITICIDE | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
| US-3932630-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932629-A | Triazolyl phosphorus esters as pesticides | CIBA-GEIGY CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932632-A | Insecticidal compositions containing an organophosphorus compound and a thiolcarbamate | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269213-A1 | 8-Hydroxyquinoline compounds and methods thereof | MMP8, MMP26, MMP9 | POLB 1708/4885GPBAR1 1074/4885ALDH1A1 406/4885 |
| US-20210352892-A1 | MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT | ACP1, PTMS, VDAC1 | POLB 1662/4885GPBAR1 4785/4885ALDH1A1 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.