SCHEMBL18201429

SCHEMBL18201429

c1ccc2cc(Nc3cccc4c3sc3ccccc34)ccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
CYP3A4 P08684 3/20 0.45
HSD17B10 Q99714 3/20 0.45
HPGD P15428 2/20 0.45
MAPK14 Q16539 2/20 0.42
FADS1 O60427 1/20 0.41
PARP14 Q460N5 1/20 0.41
EPHX2 P34913 1/20 0.40
RAB9A P51151 2/20 0.40
TP53 P04637 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
CDC25B P30305 1/20 0.40
ATM Q13315 1/20 0.40
EGFR P00533 1/20 0.40
PTGIR P43119 1/20 0.39
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31690686 0.89 ALOX5 (0.40) ALDH1A1CYP3A4HSD17B10HPGDFADS1
SCHEMBL23822222 0.89 ALOX5 (0.40) ALDH1A1CYP3A4HSD17B10HPGDFADS1
SCHEMBL17383277 0.87 ALDH1A1 (0.44) ALDH1A1CYP3A4HSD17B10HPGDMAPK14
SCHEMBL21234626 0.87 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDMAPK14
SCHEMBL23179576 0.87 ALOX5 (0.39) ALDH1A1CYP3A4HSD17B10HPGDPARP14
SCHEMBL29303801 0.87 FADS1 (0.39) ALDH1A1CYP3A4HSD17B10HPGDFADS1
SCHEMBL18311793 0.86 PTGIR (0.51) ALDH1A1CYP3A4HSD17B10HPGDFADS1
SCHEMBL17383122 0.86 MAPK14 (0.43) ALDH1A1CYP3A4HSD17B10HPGDMAPK14
SCHEMBL18201519 0.85 MAPT (0.45) ALDH1A1CYP3A4HSD17B10HPGDMAPK14
SCHEMBL23637467 0.83 MAPK14 (0.41) ALDH1A1CYP3A4HSD17B10HPGDMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022262365-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE COMPRISING SAME 陕西莱特光电材料股份有限公司 2022-12-22 WO disclosed
WO-2016175533-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-11-03 WO disclosed