Sugi Predict

Sugi Predict / Compounds / Phosphine

Phosphine

Phosphine

SCHEMBL1820375

P.P.c1ccc2c(-c3cccc4ccccc34)cccc2c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.56
▸ HSD17B10 Q99714 7/20 0.56
▸ TSHR P16473 5/20 0.56
▸ CYP2A6 P11509 3/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ HPGD P15428 4/20 0.50
▸ CYP1A2 P05177 3/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ KEAP1 Q14145 1/20 0.50
▸ HPRT1 P00492 1/20 0.50
▸ KDM4E B2RXH2 2/20 0.48
▸ PTPN1 P18031 1/20 0.48
▸ ALPL P05186 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ MAPK1 P28482 3/20 0.48
▸ L3MBTL1 Q9Y468 3/20 0.48
▸ ATM Q13315 2/20 0.48
▸ NISCH Q9Y2I1 1/20 0.47
▸ POLB P06746 1/20 0.46
▸ HIF1A Q16665 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL29018216 1.00 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phosphine SCHEMBL6665557 1.00 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Phosphine SCHEMBL9249650 0.97 ALDH1A1 (0.53) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL25302086 0.97 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL27953 0.97 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL29350007 0.97 ALDH1A1 (0.59) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL17836548 0.94 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Hydrochloric Acid SCHEMBL4268575 0.94 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
Ammonia Solution, Strong SCHEMBL3156160 0.94 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1
SCHEMBL6077039 0.94 ALDH1A1 (0.56) ALDH1A1HSD17B10TSHRCYP2A6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011894-B1 PLATINUM COMPLEXES WITH BINAPHTHYL DIPHOSPHINE LIGANDS FOR THE CATALYSIS OF HYDROXY CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS EVONIK OPERATIONS GMBH (DE) 2023-05-31 — — EP disclosed
CN-115124460-A Dinaphthalene axis chiral ligand containing coordination unit and preparation method and application thereof 华东理工大学 2022-09-30 — — CN disclosed
EP-2560959-B1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2014-08-20 — — EP disclosed
EP-2560960-B1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2014-02-26 — — EP disclosed
US-8524915-B2 Process for the preparation of pyrazole carboxylic acid amides SYNGENTA CROP PROTECTION LLC (US) 2013-09-03 — — US disclosed
US-8519152-B2 Process for the preparation of pyrazole carboxylic acid amides SYNGENTA CROP PROTECTION LLC (US) 2013-08-27 — — US disclosed
US-8519151-B2 Process for the preparation of pyrazole carboxylic acid amides SYNGENTA CROP PROTECTION LLC (US) 2013-08-27 — — US disclosed
EP-2316813-B1 Process for the preparation of amines SYNGENTA PARTICIPATIONS AG (CH) 2013-04-03 — — EP disclosed
EP-2560959-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES Syngenta Participations AG (CH) 2013-02-27 — — EP disclosed
EP-2560960-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES Syngenta Participations AG (CH) 2013-02-27 — — EP disclosed
WO-2011131546-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-10-27 — — WO disclosed
WO-2011131545-A1 PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-10-27 — — WO disclosed
EP-2316814-A1 Process for preparation of halogen substituted benzonorbornenes derivatives Syngenta Participations AG (CH) 2011-05-04 — — EP disclosed
EP-2316813-A1 Process for the preparation of amines Syngenta Participations AG (CH) 2011-05-04 — — EP disclosed
EP-2316815-A1 Process for preparation of halogen substituted arynes Syngenta Participations AG (CH) 2011-05-04 — — EP disclosed
EP-2316809-A1 Process for the preparation of benzonorbornane derivatives Syngenta Participations AG (CH) 2011-05-04 — — EP disclosed
US-7781615-B2 Process for the preparation of amines SYNGENTA CROP PROTECTION, INC. (US) 2010-08-24 — — US disclosed
US-20090221856-A1 PROCESS FOR THE PREPARATION OF AMINES SYNGENTA CROP PROTECTION, INC. (US) 2009-09-03 — — US disclosed
EP-1963251-A2 PROCESS FOR THE PREPARATION OF AMINES Syngeta Participations AG (CH) 2008-09-03 — — EP disclosed
WO-2007068417-A2 PROCESS FOR THE PREPARATION OF AMINES SYNGENTA PARTICIPATIONS AG (CH) 2007-06-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221856-A1 PROCESS FOR THE PREPARATION OF AMINES HRH3, PAH, C1R ALDH1A1 1504/4885HSD17B10 382/4885TSHR 838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.