Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5656613 | 0.83 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL29013549 | 0.83 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4ACHETDP1 | |
| SCHEMBL11898141 | 0.83 | POLB (0.48) | TDP1MAPK1 | |
| SCHEMBL12573008 | 0.79 | HCAR2 (0.41) | — | |
| SCHEMBL31384688 | 0.79 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL14539606 | 0.78 | ALDH1A1 (0.49) | SLC6A3SLC6A2SLC6A4MAPK1 | |
| SCHEMBL5658248 | 0.78 | ALDH1A1 (0.49) | SLC6A3SLC6A2SLC6A4MAPK1 | |
| SCHEMBL8636289 | 0.77 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4ACHE | |
| SCHEMBL19645298 | 0.76 | ACHE (0.34) | ACHE | |
| SCHEMBL5656195 | 0.76 | ATR (0.39) | SLC6A3SLC6A2SLC6A4ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299437-B | Octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-109071567-B | Anti-influenza small molecule compound and preparation method and application thereof | 四川大学 | 2021-03-23 | — | — | CN | disclosed |
| US-8471010-B2 | Synthesis of dihydrothieno[3,2-d]pyrimidine diols | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8471010-B2 | Synthesis of dihydrothieno[3,2-d]pyrimidine diols | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-25 | — | — | US | disclosed |
| EP-2315755-B1 | SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INT (DE) | 2012-08-08 | — | — | EP | disclosed |
| US-20110130563-A1 | SYNTHESIS IF DIHYDROTHIENO[3,2-D]PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-02 | — | — | US | disclosed |
| US-20110130563-A1 | SYNTHESIS IF DIHYDROTHIENO[3,2-D]PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-02 | — | — | US | disclosed |
| EP-2315755-A2 | SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS | Boehringer Ingelheim International GmbH (DE) | 2011-05-04 | — | — | EP | disclosed |
| WO-2009140127-A2 | SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009140127-A2 | SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110130563-A1 | SYNTHESIS IF DIHYDROTHIENO[3,2-D]PYRIMIDINE DIOLS | DPYD, DHODH, PDE4B | SLC6A3 1466/4885SLC6A2 2547/4885SLC6A4 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.