Fluoride Ion

Fluoride Ion

SCHEMBL1820565

[F-].[F-].c1ccc2c(c1)-c1ccccc1C2[Ti+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.42
HTR2A P28223 2/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
POLB P06746 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ACHE P22303 3/20 0.34
BCHE P06276 2/20 0.34
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1821842 0.94 GPR3 (0.42) GPR3HTR2ACYP1A2CYP2D6HDAC3
SCHEMBL8383636 0.94 GPR3 (0.42) GPR3HTR2ACYP1A2CYP2D6HDAC3
Hydrochloric Acid SCHEMBL395593 0.94 GPR3 (0.42) GPR3HTR2ACYP1A2CYP2D6HDAC3
SCHEMBL7034053 0.90 GPR3 (0.44) GPR3HTR2ACYP1A2CYP2D6HDAC3
Fluoride Ion SCHEMBL5184093 0.76 HTR6 (0.33) GPR3HTR2ACYP1A2CYP2D6CHRM2
Hydrochloric Acid SCHEMBL1116212 0.73 GPR3 (0.35) GPR3HTR2AALDH1A1ACHEMEN1
Hydrochloric Acid SCHEMBL16144801 0.72 GPR3 (0.34) GPR3HTR2AGAA
Fluoride Ion SCHEMBL3384407 0.71 GPR3 (0.46) GPR3HTR2ACYP1A2CYP2D6HDAC3
SCHEMBL1501579 0.71 GPR3 (0.46) GPR3HTR2ACYP1A2CYP2D6HDAC3
SCHEMBL27885617 0.71 HTR2A (0.52) GPR3HTR2ACYP1A2CYP2D6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US claimed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP claimed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US claimed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP claimed
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed