Hydrochloric Acid

Hydrochloric Acid

SCHEMBL395593

[Cl-].[Cl-].c1ccc2c(c1)-c1ccccc1C2[Ti+2]C1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.34
CHRM2 known ✓ P08172 1/20 0.34
CHRM1 known ✓ P11229 1/20 0.34
SLC6A2 known ✓ P23975 1/20 0.34
SLC6A3 known ✓ Q01959 1/20 0.34
GPR3 P46089 2/20 0.42
HTR2A P28223 2/20 0.42
CYP19A1 P11511 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
POLB P06746 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
BCHE P06276 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1821842 0.94 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL8383636 0.94 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
Fluoride Ion SCHEMBL1820565 0.94 GPR3 (0.42) GPR3HTR2ACYP19A1HDAC3HDAC4
SCHEMBL7034053 0.90 GPR3 (0.44) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL1116212 0.77 GPR3 (0.35) GPR3HTR2AACHEKMT2AMEN1
Hydrochloric Acid SCHEMBL16144801 0.77 GPR3 (0.34) GPR3HTR2AGAA
Hydrochloric Acid SCHEMBL395754 0.76 HTR6 (0.33) GPR3HTR2ACYP2D6CHRM2CHRM1
Hydrochloric Acid SCHEMBL7822603 0.74 ALDH1A1 (0.38) GPR3POLBCYP1A2CYP2D6KMT2A
Hydrochloric Acid SCHEMBL5606839 0.74 HTR2A (0.40) GPR3HTR2ACYP19A1HDAC3HDAC4
Hydrochloric Acid SCHEMBL3385863 0.71 GPR3 (0.46) GPR3HTR2ACYP19A1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US claimed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP claimed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP claimed
EP-3255066-B1 METHOD FOR PRODUCING METALLOCENE-SUPPORTED CATALYST LG CHEMICAL LTD (KR) 2021-05-19 EP disclosed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP disclosed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US disclosed
EP-3106474-B1 METHOD OF PREPARING A POLYOLEFIN LG CHEMICAL LTD (KR) 2018-12-26 EP disclosed
US-9988469-B2 Method for preparing polyolefin and polyolefin prepared thereby LG CHEM, LTD. (KR) 2018-06-05 US disclosed
US-9975969-B2 Method of preparing polyolefin, and polyolefin prepared thereby LG CHEM, LTD. (KR) 2018-05-22 US disclosed
US-20180094084-A1 METHOD OF PREPARING SUPPORTED METALLOCENE CATALYST LG CHEM, LTD. (KR) 2018-04-05 US disclosed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US disclosed
EP-1026176-A1 CATALYST FOR OLEFIN POLYMER PRODUCTION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-08-09 EP disclosed
EP-0996647-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 2000-05-03 EP disclosed
EP-0985673-A2 Modified aluminium oxy compound, polymerization catalyst and process for producing olefin polymer and alkenyl aromatic hydrocarbon polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-03-15 EP disclosed
EP-0984016-A1 ALUMINUM COMPOUND AND PROCESS FOR PRODUCING THE SAME, CATALYST FOR OLEFIN POLYMER PRODUCTION, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-03-08 EP disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed
US-5916982-A Process for the production of polyolefins NIPPON OIL CO., LTD. (JP) 1999-06-29 US disclosed
WO-1999003897-A1 PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS HAVING A DESIRABLE MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 1999-01-28 WO disclosed
EP-0768320-A1 Catalyst component and catalyst NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed
EP-0768319-A1 Process for the production of polyolefins NIPPON OIL CO. LTD. (JP) 1997-04-16 EP disclosed