Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 18/20 | 0.95 |
| ▸ | MTOR | P42345 | 1/20 | 0.95 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.95 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.95 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gpi-1046 SCHEMBL2542494 | 0.97 | FKBP1A (0.96) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL4766380 | 0.97 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL7187 | 0.97 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL7324245 | 0.96 | FKBP1A (0.98) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL2191097 | 0.96 | FKBP1A (0.98) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL5965941 | 0.95 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7246114 | 0.92 | FKBP1A (0.90) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL2537059 | 0.92 | FKBP1A (0.89) | FKBP1AMTORFKBP4FKBP5 | |
| Gpi-1046 SCHEMBL19386253 | 0.91 | FKBP1A (0.87) | FKBP1AMTORFKBP4FKBP5 | |
| SCHEMBL7767569 | 0.89 | FKBP1A (1.00) | FKBP1AMTORFKBP4FKBP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2232257-B1 | STABILIZATION OF SOLID SUPPORT ASSAY REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC (US) | 2018-11-21 | — | — | EP | disclosed |
| EP-1687283-B1 | METHOD FOR DETERMINING FK506 | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2012-01-04 | — | — | EP | disclosed |
| US-7842475-B2 | a dry assay reagent, which comprises a solid support and one or more molecules of a receptor immobilized on the solid support; bioassay | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-11-30 | — | — | US | disclosed |
| EP-2232257-A1 | STABILIZATION OF SOLID SUPPORT ASSAY REAGENTS | Siemens Healthcare Diagnostics Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009089262-A1 | STABILIZATION OF SOLID SUPPORT ASSAY REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-07-16 | — | — | WO | disclosed |
| US-20090176213-A1 | STABILIZATION OF SOLID SUPPORT ASSAY REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC., A CORPORATION OF CALIFORNIA (US) | 2009-07-09 | — | — | US | disclosed |
| EP-1687283-A4 | METHOD AND COMPOSITION USEFUL FOR DETERMINING FK 506 | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2008-09-24 | — | — | EP | disclosed |
| EP-1687283-A2 | METHOD AND COMPOSITION USEFUL FOR DETERMINING FK 506 | Dade Behring Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005052542-A2 | METHOD AND COMPOSITION USEFUL FOR DETERMINING FK 506 | DADE BEHRING INC. (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050112778-A1 | Method and composition useful for determining FK 506 | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 2005-05-26 | — | — | US | disclosed |
| EP-0833894-A1 | RAPAMCYCIN-BASED REGULATION OF BIOLOGICAL EVENTS | ARIAD GENE THERAPEUTICS, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041865-A1 | RAPAMCYCIN-BASED REGULATION OF BIOLOGICAL EVENTS | ARIAD GENE THERAPEUTICS, INC. (US) | 1996-12-27 | — | — | WO | disclosed |
| CN-1130401-A | Regulated apoptosis | UNIV LELAND STANFORD JUNIOR (US) | 1996-09-04 | — | — | CN | disclosed |