Gpi-1046

Gpi-1046

SCHEMBL2191097

CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCc1cccnc1.[PbH2]

nearest known ligand 0.98

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 18/20 0.98
MTOR P42345 1/20 0.98
FKBP4 Q02790 1/20 0.98
FKBP5 Q13451 1/20 0.98

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gpi-1046 SCHEMBL7187 0.99 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL4766380 0.99 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL7324245 0.98 FKBP1A (0.98) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL2542494 0.97 FKBP1A (0.96) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL182073 0.96 FKBP1A (0.95) FKBP1AMTORFKBP4FKBP5
SCHEMBL5965941 0.96 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5
SCHEMBL7246114 0.94 FKBP1A (0.90) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL2537059 0.93 FKBP1A (0.89) FKBP1AMTORFKBP4FKBP5
Gpi-1046 SCHEMBL19386253 0.93 FKBP1A (0.87) FKBP1AMTORFKBP4FKBP5
SCHEMBL7767569 0.91 FKBP1A (1.00) FKBP1AMTORFKBP4FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2353686-B1 METHOD FOR PURIFYING FK506 BY EXTRACTION WITH SILVER ION SOLUTION GENOTECH CORP (KR) 2016-11-09 EP disclosed
US-8193345-B2 Purification method of lactone compounds containing unsaturated alkyl group by extraction with silver ion solution GENOTECH CORP. (KR) 2012-06-05 US disclosed
EP-2353686-A1 METHOD FOR PURIFYING LACTONE COMPOUND HAVING UNSATURATED ALKYL GROUP BY EXTRACTION WITH SILVER ION SOLUTION Genotech Co., Ltd (KR) 2011-08-10 EP disclosed
US-20110172413-A1 PURIFICATION METHOD OF LACTONE COMPOUNDS CONTAINING UNSATURATED ALKYL GROUP BY EXTRACTION WITH SILVER ION SOLUTION GENOTECH CO., LTD (KR) 2011-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172413-A1 PURIFICATION METHOD OF LACTONE COMPOUNDS CONTAINING UNSATURATED ALKYL GROUP BY EXTRACTION WITH SILVER ION SOLUTION FKBP2, FKBP8, FKBP5 FKBP1A 8/4885MTOR 154/4885FKBP4 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.