SCHEMBL1820741

SCHEMBL1820741

Sc1ncnc2c1ncn2-n1cnc2cncnc21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 1/20 0.35
▸ HDAC1 Q13547 1/20 0.32
▸ HDAC6 Q9UBN7 1/20 0.32
▸ LTA4H P09960 1/20 0.31
▸ MKNK2 Q9HBH9 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ LMNA P02545 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2C9 P11712 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30
▸ HBB P68871 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683802 0.84 ADORA2A (0.35) CYP1A2
SCHEMBL120720 0.81 ADORA2A (0.49) —
SCHEMBL6959953 0.81 FDPS (0.38) FDPSHDAC1HDAC6LTA4HMEN1
SCHEMBL28340215 0.80 FDPS (0.44) FDPSHDAC1HDAC6LTA4HMKNK2
SCHEMBL6036330 0.71 CDK1 (0.44) FDPS
SCHEMBL27734755 0.70 FDPS (0.40) FDPSHDAC1HDAC6LTA4HMKNK2
SCHEMBL1748495 0.70 FDPS (0.37) FDPSHDAC1HDAC6LTA4HMKNK2
SCHEMBL7797362 0.70 FDPS (0.37) FDPSHDAC1HDAC6LTA4HMKNK2
SCHEMBL27558464 0.70 FDPS (0.37) FDPSHDAC1HDAC6LTA4HMKNK2
SCHEMBL6055010 0.69 FDPS (0.39) FDPSHDAC1HDAC6LTA4HMKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117441022-A Sequential electroporation method 美克斯细胞有限公司 2024-01-23 — — CN disclosed
CN-116916968-A Oligonucleotide-based therapeutics and uses thereof 托德·斯皮尔 2023-10-20 — — CN disclosed
US-20220211621-A1 LIPOSOMAL SUSTAINED-RELEASE COMPOSITIONS CONTAINING A THERAPEUTIC DRUG AND USE THEREOF TLC BIOPHARMACEUTICALS, INC. 2022-07-07 — — US disclosed
CN-107811971-B Liposomes for drug delivery 益普生生物制药公司 2021-10-29 — — CN disclosed
WO-2020220000-A1 LIPOSOMAL SUSTAINED-RELEASE COMPOSITIONS CONTAINING A THERAPEUTIC DRUG AND USE THEREOF TLC BIOPHARMACEUTICALS, INC. (US) 2020-10-29 — — WO disclosed
US-10363031-B2 Tissue thickness compensators for surgical staplers ETHICON LLC (US) 2019-07-30 — — US disclosed
US-20160287249-A1 TISSUE THICKNESS COMPENSATORS FOR CIRCULAR SURGICAL STAPLERS CILAG GMBH INTERNATIONAL (CH) 2016-10-06 — — US disclosed
US-9364233-B2 Tissue thickness compensators for circular surgical staplers ETHICON ENDO-SURGERY, LLC (US) 2016-06-14 — — US disclosed
US-20120241505-A1 TISSUE THICKNESS COMPENSATORS FOR CIRCULAR SURGICAL STAPLERS ETHICON ENDO-SURGERY, INC. (US) 2012-09-27 — — US disclosed
EP-2338525-A2 Remote detection of substance delivery to cells California Pacific Medical Center (US) 2011-06-29 — — EP disclosed
EP-1648299-A4 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS CALIFORNIA PACIFIC MED CENTER (US) 2008-10-22 — — EP disclosed
CN-1878594-A Electrical devices and anti-scarring agents ANGIOTECH INT AG (CH) 2006-12-13 — — CN disclosed
CN-1878514-A Soft tissue implants and anti-scarring agents ANGIOTECH INT AG (CH) 2006-12-13 — — CN disclosed
EP-1648299-A1 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS California Pacific Medical Center (US) 2006-04-26 — — EP disclosed
CN-1688349-A Compositions and methods for coating medical implants ANGIOTECH PHARM INC (CH) 2005-10-26 — — CN disclosed
US-20050112065-A1 Remote detection of substance delivery to cells SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER 2005-05-26 — — US disclosed
WO-2005016141-A1 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS CALIFORNIA PACIFIC MEDICAL CENTER (US) 2005-02-24 — — WO disclosed
EP-1299084-A2 LIPOSOMAL ANTINEOPLASTIC DRUGS AND USES THEREOF Inex Pharmaceuticals Corp. (CA) 2003-04-09 — — EP disclosed
WO-2002002077-A2 LIPOSOMAL ANTINEOPLASTIC DRUGS AND USES THEREOF INEX PHARMACEUTICALS CORPORATION (CA) 2002-01-10 — — WO disclosed
US-4902717-A TREATMENT OF ESTROGEN DEPENDENT NEOPLASTIC DISEASE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-02-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211621-A1 LIPOSOMAL SUSTAINED-RELEASE COMPOSITIONS CONTAINING A THERAPEUTIC DRUG AND USE THEREOF LIPA, LPXN, SGMS2 FDPS 1890/4885HDAC1 2878/4885HDAC6 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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