SCHEMBL18207643

SCHEMBL18207643

Fc1ccc2ccc(C(F)(F)F)[c]c2c1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
AHR P35869 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL456001 0.75 ALDH1A1 (0.32)
SCHEMBL6066739 0.74 CYP2A6 (0.34) CYP1A2CYP2A6
SCHEMBL29045253 0.74 CYP1A2 (0.41) CYP1A2CYP2A6AHR
SCHEMBL5657674 0.65 KDM5A (0.35)
SCHEMBL21385087 0.65 CYP1A2 (0.52) CYP1A2CYP2A6AHR
SCHEMBL6066540 0.64 HPRT1 (0.45) CYP1A2CYP2A6AHR
SCHEMBL644839 0.63 CYP1A2 (0.48) CYP1A2CYP2A6AHR
SCHEMBL209074 0.61 BACE1 (0.38) CYP1A2CYP2A6AHR
SCHEMBL457243 0.61
SCHEMBL262756 0.61 NT5E (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9730449-B2 Thiazole compound and its use in pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-15 US disclosed
EP-3093286-A1 THIAZOLE COMPOUNDS AND PEST CONTROL APPLICATIONS THEREOF Sumitomo Chemical Co., Ltd (JP) 2016-11-16 EP disclosed
US-20160324155-A1 THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-11-10 US disclosed
CN-105873911-A Thiazole compounds and pest control applications thereof 住友化学株式会社 2016-08-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160324155-A1 THIAZOLE COMPOUND AND ITS USE IN PEST CONTROL TRPA1, NAT1, TAS2R1 CYP1A2 291/4885CYP2A6 1235/4885AHR 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.