Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243595 | 0.73 | VNN1 (0.43) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL22190045 | 0.72 | SMN1; SMN2 (0.62) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| Methane SCHEMBL29238356 | 0.71 | SMN1; SMN2 (0.60) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL1081535 | 0.68 | CYP1A2 (0.47) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL1712450 | 0.68 | CYP1A2 (0.47) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL1712531 | 0.68 | CYP1A2 (0.47) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL1712451 | 0.68 | CYP1A2 (0.47) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8064648 | 0.67 | CYP1A2 (0.46) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL2089243 | 0.67 | CYP1A2 (0.70) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 | |
| SCHEMBL2089245 | 0.67 | CYP1A2 (0.70) | HIF1ASMN1; SMN2CYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016179140-A1 | FIBROBLAST GROWTH FACTOR POLYMERS, METHODS FOR MAKING THE SAME AND APPLICATIONS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-10 | — | — | WO | disclosed |