Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | ARG1 | P05089 | 1/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL29238356 | 0.98 | SMN1; SMN2 (0.60) | SMN1; SMN2HIF1ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL20268313 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACYP1A2KIF11MEN1 | |
| SCHEMBL20290815 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACYP1A2SLC6A2KIF11 | |
| SCHEMBL20268310 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACYP1A2KIF11MEN1 | |
| SCHEMBL20290780 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2HIF1ACYP1A2SLC6A2TAAR1 | |
| SCHEMBL27979604 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2HIF1ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL29415188 | 0.85 | MMP1 (0.50) | SMN1; SMN2HIF1A | |
| SCHEMBL20290760 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2HIF1ACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8775713 | 0.84 | KIF11 (0.47) | SMN1; SMN2HIF1AKIF11KMT2ACES2 | |
| SCHEMBL8504875 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2HIF1ACYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791431-A | Dihydro-isoquinolone compounds and isoindoles Selective synthesis method of pinone compound | 常州大学 | 2024-10-18 | — | — | CN | claimed |
| CN-102264734-B | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA | 2015-06-17 | — | — | CN | claimed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | claimed |
| CN-118791431-A | Dihydro-isoquinolone compounds and isoindoles Selective synthesis method of pinone compound | 常州大学 | 2024-10-18 | — | — | CN | disclosed |
| US-12077611-B2 | Cyclic peptides multimers targeting α4β7 integrin | ZEALAND PHARMA A/S (DK) | 2024-09-03 | — | — | US | disclosed |
| US-20230406884-A1 | CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2023-12-21 | — | — | US | disclosed |
| US-11713338-B2 | Cyclic peptides multimers targeting α-4-β-7 integrin | ZEALAND PHARMA A/S (DK) | 2023-08-01 | — | — | US | disclosed |
| US-11111273-B2 | Cyclic peptides multimers targeting alpha-4-beta-7 integrin | ZEALAND PHARMA A/S (DK) | 2021-09-07 | — | — | US | disclosed |
| US-20200216501-A1 | CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN | ZEALAND PHARMA A/S (DK) | 2020-07-09 | — | — | US | disclosed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | disclosed |
| CN-1518445-A | Treatment of sexual dysfunction | 沃纳-兰伯特公司 | 2004-08-04 | — | — | CN | disclosed |
| CN-1479618-A | Treatment of sexual dysfunction with bombesin antagonists | ����-�����ع�˾ | 2004-03-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11111273-B2 | Cyclic peptides multimers targeting alpha-4-beta-7 integrin | ITGB7, ITGB4, ITGA4 | SMN1; SMN2 3111/4885HIF1A 1733/4885CYP1A2 4768/4885 |
| US-12077611-B2 | Cyclic peptides multimers targeting α4β7 integrin | ITGB7, ITGB4, ITGA4 | SMN1; SMN2 3171/4885HIF1A 2295/4885CYP1A2 4501/4885 |
| US-20200216501-A1 | CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN | ITGB7, ITGB4, ITGA4 | SMN1; SMN2 3111/4885HIF1A 1733/4885CYP1A2 4768/4885 |
| US-20230406884-A1 | CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN | ITGB7, ITGB4, ITGA4 | SMN1; SMN2 3111/4885HIF1A 1733/4885CYP1A2 4768/4885 |
| US-11713338-B2 | Cyclic peptides multimers targeting α-4-β-7 integrin | ITGB7, ITGB4, ITGA4 | SMN1; SMN2 3181/4885HIF1A 1611/4885CYP1A2 4762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.