Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823617 | 0.83 | VNN1 (0.46) | VNN1CYP2C9NAMPTIDO1CYP1A2 | |
| SCHEMBL7823614 | 0.83 | VNN1 (0.46) | VNN1CYP2C9NAMPTIDO1CYP1A2 | |
| SCHEMBL30317231 | 0.82 | NAMPT (0.37) | VNN1CYP2C9NAMPTIDO1SMN1; SMN2 | |
| SCHEMBL9302445 | 0.78 | VNN1 (0.42) | VNN1CYP2C9NAMPTIDO1CYP1A2 | |
| SCHEMBL9302450 | 0.78 | VNN1 (0.42) | VNN1CYP2C9NAMPTIDO1CYP1A2 | |
| SCHEMBL8309619 | 0.76 | VNN1 (0.38) | VNN1CYP2C9NAMPTIDO1CYP1A2 | |
| SCHEMBL9661853 | 0.74 | KCNA5 (0.44) | VNN1CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9661857 | 0.74 | KCNA5 (0.44) | VNN1CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18209207 | 0.73 | HIF1A (0.37) | CYP1A2CYP2C19HIF1ASMN1; SMN2GRM5 | |
| SCHEMBL5529411 | 0.72 | CYP3A4 (0.36) | VNN1CYP2C9NAMPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | claimed |
| WO-2010003084-A2 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-01-07 | — | — | WO | disclosed |