Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | GUSB | P08236 | 3/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375730 | 0.77 | MAOA (0.65) | MAOAMAOBGUSBCYP2C9ATM | |
| Hydrochloric Acid SCHEMBL28094942 | 0.76 | MAOA (0.49) | MAOAMAOBGUSBNTSR1GPR55 | |
| SCHEMBL2721424 | 0.74 | MAOA (0.74) | MAOAMAOBGUSBCYP2C9ATM | |
| SCHEMBL521775 | 0.74 | MAOA (1.00) | MAOAMAOBCYP2C9ATMHDAC3 | |
| SCHEMBL29419966 | 0.74 | MAOA (1.00) | MAOAMAOBCYP2C9ATMHDAC3 | |
| Hydrochloric Acid SCHEMBL28094614 | 0.73 | MAOA (0.46) | MAOAMAOBGUSBNTSR1GPR55 | |
| SCHEMBL28681589 | 0.72 | MAOA (0.95) | MAOAMAOBCYP2C9ATMHDAC3 | |
| SCHEMBL4923442 | 0.70 | MAOA (0.66) | MAOAMAOBGUSBCYP2C9ATM | |
| SCHEMBL7189875 | 0.68 | NTSR1 (0.40) | MAOAMAOBNTSR1GPR55MTNR1A | |
| SCHEMBL25424957 | 0.67 | MAOA (0.68) | MAOAMAOBGUSBCYP2C9ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170224609-A1 | Oxidation resistant dentifrice compositions | ARVANITIDOU EVANGELIA S (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170224609-A1 | Oxidation resistant dentifrice compositions | ARVANITIDOU EVANGELIA S (US) | 2017-08-10 | — | — | US | disclosed |
| EP-1838275-B1 | OXIDATION RESISTANT DENTIFRICE COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2016-11-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224609-A1 | Oxidation resistant dentifrice compositions | DNMT1, DNMT3A, CAT | MAOA 3592/4885MAOB 3569/4885GUSB 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.