SCHEMBL7189875

SCHEMBL7189875

ClC1=C(c2ccccc2)Oc2ccccc2C1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTSR1 P30989 1/20 0.40
GPR55 Q9Y2T6 1/20 0.40
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP2C9 P11712 2/20 0.38
MAPT P10636 5/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
LMNA P02545 4/20 0.33
HTT P42858 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ATM Q13315 1/20 0.33
MTNR1A P48039 1/20 0.33
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
DRD2 P14416 1/20 0.32
GABRA1 P14867 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7564377 0.77 MAOA (0.43) MAOAMAOBCYP2C9MAPTMEN1
SCHEMBL7997285 0.77 MAOA (0.43) MAOAMAOBCYP2C9MAPTMEN1
SCHEMBL1128327 0.74 MAOA (0.58) MAOAMAOBCYP2C9MAPTMEN1
SCHEMBL6551555 0.73 CHRM2 (0.35) MAOAMAOBMAPTMEN1KMT2A
SCHEMBL18214564 0.68 MAOA (0.57) NTSR1GPR55MAOAMAOBCYP2C9
SCHEMBL26185677 0.67 MAOA (0.45) MAOAMAOBCYP2C9MAPTMEN1
SCHEMBL4583348 0.67 LMNA (0.46) NTSR1GPR55MAOAMAOBCYP2C9
SCHEMBL3885169 0.66 TSHR (0.37) MEN1KMT2ALMNAHTR2AHTR2C
SCHEMBL9124381 0.66 AHR (0.50) MAOAMAOBCYP2C9MAPTMEN1
SCHEMBL28094786 0.65 NTSR1 (0.47) NTSR1GPR55MAOAMAOBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286748-A General method of shortening the duration of common colds by application of medicaments to tissues of oral cavity EBY III GEORGE A (US) 1994-02-15 US claimed
US-20240165021-A1 Prophylactic and Therapeutic Agents for Upper Respiratory Tract Infections Caused by Influenza and Other Enveloped Viruses BROWN AMY C (US) 2024-05-23 US disclosed
US-20160000826-A1 Gargle Method to Reduce the Duration of Common Cold Symptoms BROWN AMY C (US) 2016-01-07 US disclosed
US-9072753-B1 Gargle method to reduce the duration of common cold symptoms BROWN AMY C (US) 2015-07-07 US disclosed
US-6641801-B1 Common cold is caused by a virus. Antiviral compounds that kill viruses would then be most likely to serve as a remedy for the common cold. Invention seeks to offer a unique use of an antiviral agent, ethanol (with or without additional herbs LOVE LIVES 2003-11-04 US disclosed
US-5286748-A General method of shortening the duration of common colds by application of medicaments to tissues of oral cavity EBY III GEORGE A (US) 1994-02-15 US disclosed