Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18215475 | 0.71 | LMNA (0.36) | LMNA | |
| SCHEMBL18215559 | 0.69 | LMNA (0.35) | LMNA | |
| SCHEMBL1097900 | 0.67 | — | — | |
| SCHEMBL18507948 | 0.63 | LMNA (0.41) | LMNA | |
| SCHEMBL18312537 | 0.63 | — | — | |
| SCHEMBL9482451 | 0.63 | — | — | |
| SCHEMBL18312468 | 0.60 | MMP1 (0.34) | LMNA | |
| SCHEMBL1069310 | 0.60 | — | — | |
| SCHEMBL20455 | 0.59 | — | — | |
| SCHEMBL12124909 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016179343-A1 | DIHYDRO-2H-BENZO[b][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORy AND THE TREATMENT OF DISEASE | LYCERA CORPORATION (US) | 2016-11-10 | — | — | WO | disclosed |