SCHEMBL18216712

SCHEMBL18216712

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3c(-c5ccc6oc7ccccc7c6c5)cccc34)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
GGPS1 O95749 1/20 0.41
PLA2G2A P14555 2/20 0.40
PLA2G4A P47712 2/20 0.40
PLA2G10 O15496 1/20 0.40
PRKDC P78527 2/20 0.39
PTGES2 Q9H7Z7 1/20 0.39
MAPT P10636 6/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 3/20 0.38
POLB P06746 1/20 0.38
NPC1 O15118 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
CHEK2 O96017 1/20 0.38
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23349693 1.00 ALOX5 (0.51) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL25458382 0.99 ALOX5 (0.50) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349692 0.99 ALOX5 (0.53) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349638 0.97 ALOX5 (0.54) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349499 0.97 ALOX5 (0.54) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349725 0.96 ALOX5 (0.48) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349695 0.96 ALOX5 (0.48) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL18216744 0.96 ALOX5 (0.52) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL23349699 0.96 ALOX5 (0.56) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL24217141 0.96 ALOX5 (0.56) ALOX5GGPS1PLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
WO-2022025714-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2022-02-03 WO disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-11-10 US disclosed
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD1, OXER1, OR10J3 ALOX5 525/4885GGPS1 801/4885PLA2G2A 4303/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 ALOX5 1552/4885GGPS1 1923/4885PLA2G2A 3486/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 ALOX5 1931/4885GGPS1 1048/4885PLA2G2A 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.