SCHEMBL18216730

SCHEMBL18216730

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc5c4oc4c(-c6cccc7c6oc6ccccc67)cccc45)c3)n2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.55
GGPS1 O95749 1/20 0.46
PTGES2 Q9H7Z7 1/20 0.43
PRKDC P78527 5/20 0.42
PIK3CD O00329 1/20 0.42
PIK3CB P42338 1/20 0.42
MAPT P10636 6/20 0.41
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
POLB P06746 2/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 2/20 0.40
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
USP2 O75604 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21168062 0.97 ALOX5 (0.57) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL21563826 0.97 ALOX5 (0.57) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL17232186 0.97 ALOX5 (0.57) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL25557585 0.96 ALOX5 (0.53) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL19196619 0.96 ALOX5 (0.56) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL21563827 0.96 ALOX5 (0.59) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL26868312 0.95 ALOX5 (0.52) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL24604391 0.94 ALOX5 (0.51) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL21563737 0.94 ALOX5 (0.55) ALOX5GGPS1PTGES2PRKDCPIK3CD
SCHEMBL21707165 0.94 ALOX5 (0.58) ALOX5GGPS1PTGES2PRKDCPIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20230172061-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-06-01 US disclosed
US-20230172061-A1 COMPOSITION FOR OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-06-01 US disclosed
EP-3770157-B1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-05-13 US disclosed
WO-2020085740-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-04-30 WO disclosed
US-20190292309-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-09-26 US disclosed
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-13 US disclosed
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-04-13 US disclosed
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-11-10 US disclosed
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160329506-A1 ORGANIC COMPOUND, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD1, OXER1, OR10J3 ALOX5 525/4885GGPS1 801/4885PTGES2 2438/4885
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same ARNT, AHR, DRD1 ALOX5 832/4885GGPS1 1496/4885PTGES2 3237/4885
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME ARNT, AHR, DRD1 ALOX5 832/4885GGPS1 1496/4885PTGES2 3237/4885
US-20170104163-A1 COMPOSITION FOR ORGANIC OPTOELECTRIC DIODE, ORGANIC OPTOELECTRIC DIODE, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 ALOX5 280/4885GGPS1 1069/4885PTGES2 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.