Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353069 | 0.91 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL7911522 | 0.91 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL5930961 | 0.91 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL15071342 | 0.91 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL15814832 | 0.90 | APP (0.50) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL3482694 | 0.88 | TDP1 (0.64) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL9784265 | 0.88 | TDP1 (0.64) | APPTDP1TSHRRAB9ANPC1 | |
| Ammonia Solution, Strong SCHEMBL9850170 | 0.85 | TDP1 (0.61) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL22109518 | 0.84 | TDP1 (0.61) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL21098621 | 0.83 | RAB9A (0.63) | APPTDP1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162987-A1 | DEGRADABLE POLYURETHANES AND COMPOSITES THEREOF | ADESSO ADVANCED MATERIALS WUHU CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| US-20180162987-A1 | DEGRADABLE POLYURETHANES AND COMPOSITES THEREOF | ADESSO ADVANCED MATERIALS WUHU CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| WO-2016177307-A1 | DEGRADABLE POLYURETHANES AND COMPOSITES THEREOF | ADESSO ADVANCED MATERIALS WUXI CO., LTD. (CN) | 2016-11-10 | — | — | WO | disclosed |