Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353069 | 1.00 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL5930961 | 1.00 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL15071342 | 1.00 | APP (0.67) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL22109518 | 0.93 | TDP1 (0.61) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL9784265 | 0.92 | TDP1 (0.64) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL3482694 | 0.92 | TDP1 (0.64) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL21098621 | 0.91 | RAB9A (0.63) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL26247403 | 0.91 | APP (0.64) | APPTDP1TSHRRAB9ANPC1 | |
| SCHEMBL18217366 | 0.91 | APP (0.58) | APPTDP1TSHRRAB9ANPC1 | |
| Water SCHEMBL29777471 | 0.90 | TDP1 (0.61) | APPTDP1TSHRRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328979-A | Thermoplastic copolyimides and composites therefrom | THE UNIVERSITY OF AKRON (US) | 1994-07-12 | — | — | US | claimed |
| US-8962784-B2 | Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| US-8962784-B2 | Isocyanate terminated macromer and formulation thereof for use as an internal adhesive or sealant | ETHICON, INC. (US) | 2015-02-24 | — | — | US | disclosed |
| EP-2358780-B1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON INC (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20100158849-A1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2010-06-24 | — | — | US | disclosed |
| US-20100158849-A1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ETHICON, INC. | 2010-06-24 | — | — | US | disclosed |
| WO-1999064041-A9 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE INC (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-1100519-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | Advanced Medicine, Inc. (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-1999064041-A1 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| EP-0708795-A4 | HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES | UNIV AKRON (US) | 1996-08-07 | — | — | EP | disclosed |
| EP-0708795-A1 | HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES | The University of Akron (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5397847-A | Polyimide blend | THE UNIVERSITY OF AKRON (US) | 1995-03-14 | — | — | US | disclosed |
| WO-1995002627-A1 | HEAT-RESISTANT POLYIMIDE BLENDS AND LAMINATES | THE UNIVERSITY OF AKRON (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5328979-A | Thermoplastic copolyimides and composites therefrom | THE UNIVERSITY OF AKRON (US) | 1994-07-12 | — | — | US | disclosed |
| US-4958001-A | LIQUID CRYSTAL DISPLAY DEVICE | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1990-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158849-A1 | ISOCYANATE TERMINATED MACROMER AND FORMULATION THEREOF FOR USE AS AN INTERNAL ADHESIVE OR SEALANT | ICAM1, ILK, MACF1 | APP 3696/4885TDP1 1867/4885TSHR 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.