SCHEMBL1353069

SCHEMBL1353069

Nc1ccc(OCCOCCOCCOc2ccc(N)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.67
TDP1 Q9NUW8 4/20 0.57
TSHR P16473 2/20 0.56
RAB9A P51151 2/20 0.55
NPC1 O15118 1/20 0.55
NFE2L2 Q16236 1/20 0.50
NCF1 P14598 6/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPK1 P28482 1/20 0.48
GAA P10253 1/20 0.48
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5930961 1.00 APP (0.67) APPTDP1TSHRRAB9ANPC1
SCHEMBL7911522 1.00 APP (0.67) APPTDP1TSHRRAB9ANPC1
SCHEMBL15071342 1.00 APP (0.67) APPTDP1TSHRRAB9ANPC1
SCHEMBL22109518 0.93 TDP1 (0.61) APPTDP1TSHRRAB9ANPC1
SCHEMBL9784265 0.92 TDP1 (0.64) APPTDP1TSHRRAB9ANPC1
SCHEMBL3482694 0.92 TDP1 (0.64) APPTDP1TSHRRAB9ANPC1
SCHEMBL21098621 0.91 RAB9A (0.63) APPTDP1TSHRRAB9ANPC1
SCHEMBL26247403 0.91 APP (0.64) APPTDP1TSHRRAB9ANPC1
SCHEMBL18217366 0.91 APP (0.58) APPTDP1TSHRRAB9ANPC1
Water SCHEMBL29777471 0.90 TDP1 (0.61) APPTDP1TSHRRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230084211-A1 MALLEABLE AND DEGRADABLE BENZOXAZINES KANEKA CORPORATION (JP) 2023-03-16 US claimed
US-5328979-A Thermoplastic copolyimides and composites therefrom THE UNIVERSITY OF AKRON (US) 1994-07-12 US claimed
JP-10030026-A None JP disclosed
JP-11209734-A None JP disclosed
US-12637543-B2 Thermoplastic-thermoset hybrid resins, methods, and uses thereof KANEKA CORPORATION (JP) 2026-05-26 US disclosed
US-12576474-B2 Modification method of polyurethane, polyurethane, polishing pad, and modification method of polishing pad KURARAY CO., LTD. (JP) 2026-03-17 US disclosed
US-12410280-B2 Synthesis, purification, and properties of ring-opened benzoxazine thermoplastic KANEKA CORPORATION (JP) 2025-09-09 US disclosed
US-20250236766-A1 POLYURETHANE FOR USE IN POLISHING LAYER, POLISHING LAYER, POLISHING PAD, AND METHOD FOR MODIFYING POLISHING LAYER KURARAY CO., LTD. (JP) 2025-07-24 US disclosed
US-20250230290-A1 CROSSLINKABLE THERMOPLASTICS KANEKA CORPORATION (JP) 2025-07-17 US disclosed
US-20250153304-A1 POLISHING LAYER, POLISHING PAD, METHOD FOR MANUFACTURING POLISHING PAD, AND POLISHING METHOD KURARAY CO., LTD. (JP) 2025-05-15 US disclosed
WO-2025063269-A1 THERMOPLASTIC POLYURETHANE 株式会社クラレ 2025-03-27 WO disclosed
US-20010030122-A1 Laminate comprising polyimide and conductor layer, multi-layer wiring board with the use of the same and process for producing the same KANEKA CORPORATION (JP) 2001-10-18 US disclosed
JP-H11209734-A LIQUID JOINT MEMBER KANEGAFUCHI CHEM IND CO LTD 1999-08-03 JP disclosed
JP-H1030026-A THERMOPLASTIC POLYIMIDE FILM KANEGAFUCHI CHEM IND CO LTD 1998-02-03 JP disclosed
US-5397847-A Polyimide blend THE UNIVERSITY OF AKRON (US) 1995-03-14 US disclosed
US-5328979-A Thermoplastic copolyimides and composites therefrom THE UNIVERSITY OF AKRON (US) 1994-07-12 US disclosed
EP-0311374-B1 DICYLCOHEXYL-3,4,3'4'-TETRA-CARBOXYLIC ACID OR DIANHYDRIDE THEREOF AND POLYAMIDE-ACID AND POLYMIDE OBTAINED THEREFROM Hitachi Chemical Co., Ltd. (JP) 1992-09-09 EP disclosed
US-5055593-A 1,3-bis(dicarboxyphenyl)-1,1,3,3-tetraphenyldisiloxane derivative, process for producing the same, and process for producing polyimide from the same HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-10-08 US disclosed
US-4958001-A LIQUID CRYSTAL DISPLAY DEVICE HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-09-18 US disclosed
EP-0311374-A2 Dicylcohexyl-3,4,3'4'-tetra-carboxylic acid or dianhydride thereof and polyamide-acid and polymide obtained therefrom Hitachi Chemical Co., Ltd. (JP) 1989-04-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576474-B2 Modification method of polyurethane, polyurethane, polishing pad, and modification method of polishing pad PADI2, PADI1, DUOX2 APP 2294/4885TDP1 396/4885TSHR 2789/4885
US-12637543-B2 Thermoplastic-thermoset hybrid resins, methods, and uses thereof HSF1, PBRM1, SMCHD1 APP 3860/4885TDP1 1885/4885TSHR 4127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.