SCHEMBL1821809

SCHEMBL1821809

CCCCCC([Si](OCCC)(OCCC)OCCC)[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.36
FDPS P14324 4/20 0.35
LMNA P02545 1/20 0.33
DNM1 Q05193 2/20 0.32
SMPD1 P17405 3/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
TSHR P16473 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8512723 0.93 DNM1 (0.33) FDPSDNM1
SCHEMBL15333745 0.91 OPRM1 (0.36) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15333150 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15332121 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15332687 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15333737 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15334113 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15334312 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL15333330 0.89 FDPS (0.38) OPRM1FDPSLMNADNM1SMPD1
SCHEMBL305600 0.84 OPRM1 (0.42) OPRM1FDPSLMNADNM1SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012139965-A1 CYANOACRYLATE ADHESIVE WITH IMPROVED WATER RESISTANCE HENKEL IRELAND LTD. (IE) 2012-10-18 WO claimed
US-9181356-B2 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORPORATION (TW) 2015-11-10 US disclosed
EP-2316862-B1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP (TW) 2013-12-25 EP disclosed
WO-2012139965-A1 CYANOACRYLATE ADHESIVE WITH IMPROVED WATER RESISTANCE HENKEL IRELAND LTD. (IE) 2012-10-18 WO disclosed
CN-101829600-B Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2012-08-29 CN disclosed
US-20110105694-A1 HYDROGENATION CATALYST COMPOSITION AND HYDROGENATION METHOD THEREOF TSRC CORPORATION (TW) 2011-05-05 US disclosed
EP-2316862-A1 Hydrogenation catalyst composition and hydrogenation method thereof TSRC Corporation (TW) 2011-05-04 EP disclosed
CN-101829600-A Hydrogenation catalyst composition and hydrogenation method thereof TSRC CORP 2010-09-15 CN disclosed