Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963653 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| Acetone SCHEMBL8896210 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL590894 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL320222 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL13266324 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL6064611 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL590895 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| Ammonia Solution, Strong SCHEMBL21219105 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| Hydrochloric Acid SCHEMBL1323084 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CA14CA12KMT2A | |
| SCHEMBL28574653 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1CA14CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2017-06-08 | — | — | US | disclosed |
| US-20170151232-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2017-06-01 | — | — | US | disclosed |
| US-20170016138-A1 | METHOD OF PREPARING SAMPLE FOR CRYSTAL STRUCTURE ANALYSIS, METHOD OF DETERMINING ABSOLUTE CONFIGURATION OF CHIRAL COMPOUND, AND POLYNUCLEAR METAL COMPLEX MONOCRYSTAL | THE UNIVERSITY OF TOKYO (JP) | 2017-01-19 | — | — | US | disclosed |
| US-20160326182-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | CURIA BUFFALO R&D, LLC | 2016-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160326182-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | SMN1; SMN2 252/4885ALDH1A1 66/4885CA14 2053/4885 |
| US-20170157116-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | SMN1; SMN2 252/4885ALDH1A1 66/4885CA14 2053/4885 |
| US-20170151232-A1 | METHODS AND COMPOSITIONS FOR PREVENTING OPIOID ABUSE | OPRM1, OPRK1, OPRD1 | SMN1; SMN2 252/4885ALDH1A1 66/4885CA14 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.