SCHEMBL18222911

SCHEMBL18222911

CCC1(CC)c2ccccc2-c2ccc(C(=O)C(C)=NOC(C)=O)cc21

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 14/20 0.39
▸ HTR7 P34969 3/20 0.35
▸ HTR2B P41595 3/20 0.35
▸ APEX1 P27695 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20032518 1.00 PDK2 (0.39) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL18235843 1.00 PDK2 (0.39) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL18012814 0.94 MAPT (0.38) PDK2HTR7HTR2BPOLBMAPT
SCHEMBL20032407 0.92 PDK2 (0.38) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL18235845 0.91 PDK2 (0.38) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL20032516 0.91 PDK2 (0.38) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL18122995 0.91 APEX1 (0.38) PDK2HTR7HTR2BAPEX1POLB
SCHEMBL28162990 0.90 KMT2A (0.42) PDK2MAPTSMN1; SMN2KMT2AL3MBTL1
SCHEMBL18012754 0.89 PDK2 (0.38) PDK2HTR7HTR2BAPEX1
SCHEMBL18235862 0.89 PDK2 (0.36) PDK2HTR7HTR2BAPEX1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3095778-B1 OXIME ESTER FLUORENE COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPRISING IT, PHOTORESIST COMPOSITION, USES OF THE PHOTORESIST COMPOSITION SAMYANG CORP (KR) 2020-12-16 — — EP disclosed
US-9873663-B2 Fluorenyl β-oxime ester compounds, photopolymerization initiator and photoresist composition containing the same SAMYANG CORPORATION (KR) 2018-01-23 — — US disclosed
EP-3095778-A1 NOVEL -OXIMESTER FLUORENE COMPOUND, A PHOTOPOLYMERIZATION INITIATOR COMPRISING SAME, AND PHOTORESIST COMPOSITION Samyang Corporation (KR) 2016-11-23 — — EP disclosed
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME SAMYANG CORPORATION (KR) 2016-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160332960-A1 NOVEL FLUORENYL B-OXIME ESTER COMPOUNDS, PHOTOPOLYMERIZATION INITIATOR AND PHOTORESIST COMPOSITION CONTAINING THE SAME PPOX, FTO, PFAS PDK2 981/4885HTR7 3122/4885HTR2B 1260/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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