SCHEMBL182237

SCHEMBL182237

CCC(=O)CC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
DGAT1 O75907 1/20 0.38
CYP2D6 P10635 1/20 0.37
CA12 O43570 2/20 0.35
CA14 Q9ULX7 2/20 0.35
CA1 P00915 2/20 0.35
CA7 P43166 2/20 0.35
CA2 P00918 2/20 0.35
GAA P10253 2/20 0.33
CTSK P43235 1/20 0.33
EPHX2 P34913 1/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27921361 0.98 TDP1 (0.39) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL1263607 0.96 TDP1 (0.38) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL2648388 0.87 DGAT1 (0.42) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL28129232 0.87 MGAM (0.54) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL12735830 0.85 TDP1 (0.36) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL28110392 0.84 GAA (0.45) GAACTSKMGAMSIMGAM2
SCHEMBL6415291 0.82 ALDH1A1 (0.41) DGAT1CYP2D6CA12CA14CA1
SCHEMBL241533 0.82 DGAT1 (0.46) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL10833684 0.81 TDP1 (0.38) TDP1DGAT1CYP2D6CA12CA14
SCHEMBL29438012 0.80 DGAT1 (0.41) TDP1DGAT1CYP2D6CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118638002-A Preparation method of sodium valproate toxic metabolite 2-propyl-4-pentenoic acid 湖南大学 2024-09-13 CN claimed
CN-116947600-B Preparation method of 2-isopropyl valeric acid as valproic acid process impurity 湖南省湘中制药有限公司 2024-04-26 CN claimed
CN-116874347-B Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2024-03-29 CN claimed
CN-116947600-A Preparation method of 2-isopropyl valeric acid as valproic acid process impurity 湖南省湘中制药有限公司 2023-10-27 CN claimed
CN-116874347-A Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2023-10-13 CN claimed
US-20230167310-A1 CURING CATALYST AND RESIN COMPOSITION KOEI CHEMICAL COMPANY, LIMITED (JP) 2023-06-01 US claimed
EP-4144436-A1 CURING CATALYST AND RESIN COMPOSITION Koei Chemical Company, Limited (JP) 2023-03-08 EP claimed
CN-115461147-A Curing catalyst and resin composition 广荣化学株式会社 2022-12-09 CN claimed
US-7560550-B2 Method for the production of OH protected[4-(2.6-diamino-9H-purine-9-yl)-1.3-dioxolane-2-yl]methanol derivatives RFS PHARMA, LLC (US) 2009-07-14 US claimed
CN-114930211-B Method for manufacturing polarizing film 日东电工株式会社 2024-10-29 CN disclosed
CN-118638002-A Preparation method of sodium valproate toxic metabolite 2-propyl-4-pentenoic acid 湖南大学 2024-09-13 CN disclosed
CN-112444906-B Method for manufacturing polarizing film 日东电工株式会社 2024-07-26 CN disclosed
CN-112444904-B Method for manufacturing polarizing film 日东电工株式会社 2024-07-02 CN disclosed
CN-116947600-B Preparation method of 2-isopropyl valeric acid as valproic acid process impurity 湖南省湘中制药有限公司 2024-04-26 CN disclosed
CN-1141294-A Method for prepn. of isoxazoles herbicides RHONE POULENC AGRICULTURE (GB) 1997-01-29 CN disclosed
EP-0418175-B1 Isoxazoles herbicides RHONE POULENC AGRICULTURE (GB) 1996-07-17 EP disclosed
EP-0254578-B1 ANTIBIOTIC INTERMEDIATES ELI LILLY AND COMPANY (US) 1993-09-08 EP disclosed
CN-1050188-A ISOXAZOLES HERBICIDES RHONE POULENC AGRICULTURE (GB) 1991-03-27 CN disclosed
EP-0418175-A2 Isoxazoles herbicides RHONE POULENC AGRICULTURE LTD. (GB) 1991-03-20 EP disclosed
US-4772694-A Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates ELI LILLY AND COMPANY (US) 1988-09-20 US disclosed