SCHEMBL6157096

SCHEMBL6157096

O[Si]1(O)CCCC(c2ccccc2)(c2ccccc2)O1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.36
HDAC4 P56524 2/20 0.33
DPP4 P27487 1/20 0.32
HSD11B1 P28845 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
OPRL1 P41146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182247 0.78 OPRM1 (0.35) AKR1C1DPP4OPRM1OPRK1OPRL1
Ammonia Solution, Strong SCHEMBL7597471 0.76 OPRM1 (0.34) AKR1C1DPP4OPRM1OPRK1OPRL1
SCHEMBL3365469 0.76 OPRM1 (0.34) AKR1C1DPP4OPRM1OPRK1OPRL1
SCHEMBL2352430 0.76 AKR1C1 (0.35) AKR1C1HDAC4DPP4HSD11B1
SCHEMBL29061957 0.75 DPP4 (0.34) DPP4OPRM1OPRK1OPRL1
SCHEMBL7107820 0.74 OPRM1 (0.33) AKR1C1DPP4OPRM1OPRK1OPRL1
SCHEMBL11855119 0.73 FAAH (0.31)
SCHEMBL8573142 0.71 OPRM1 (0.33) AKR1C1OPRM1OPRK1OPRL1
SCHEMBL4794587 0.71 AKR1C1 (0.31) AKR1C1
SCHEMBL18094243 0.70 SMN1; SMN2 (0.33) DPP4OPRM1OPRK1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404372-B2 Precursor for producing a polysiloxane, polysiloxane, polysiloxane resin, method of producing a polysiloxane, method of producing a polysiloxane resin, and optoelectronic component AMS-OSRAM INTERNATIONAL GMBH (DE) 2025-09-02 US claimed
US-20230287182-A1 PRECURSOR FOR PRODUCING A POLYSILOXANE, POLYSILOXANE, POLYSILOXANE RESIN, METHOD OF PRODUCING A POLYSILOXANE, METHOD OF PRODUCING A POLYSILOXANE RESIN, AND OPTOELECTRONIC COMPONENT AMS-OSRAM INTERNATIONAL GMBH (DE) 2023-09-14 US claimed
EP-0379340-B1 Heat-curable silicone rubber compositions SHINETSU CHEMICAL CO (JP) 1994-11-30 EP claimed
US-4228270-A Polyborodiphenylsiloxanes ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-10-14 US claimed
JP-8020726-A None JP disclosed
US-12404372-B2 Precursor for producing a polysiloxane, polysiloxane, polysiloxane resin, method of producing a polysiloxane, method of producing a polysiloxane resin, and optoelectronic component AMS-OSRAM INTERNATIONAL GMBH (DE) 2025-09-02 US disclosed
US-20230287182-A1 PRECURSOR FOR PRODUCING A POLYSILOXANE, POLYSILOXANE, POLYSILOXANE RESIN, METHOD OF PRODUCING A POLYSILOXANE, METHOD OF PRODUCING A POLYSILOXANE RESIN, AND OPTOELECTRONIC COMPONENT AMS-OSRAM INTERNATIONAL GMBH (DE) 2023-09-14 US disclosed
CN-115785618-A In-situ constructed core-shell type bio-based flame-retardant nanoparticle/epoxy resin composite material and preparation method thereof 广东工业大学 2023-03-14 CN disclosed
EP-1368387-B1 MICROENCAPSULATED BIOLOGICALLY ACTIVE SUBSTANCES THAT CONTAIN A WATER-SOLUBLE OR WATER-DISPERSIBLE COMB POLYMER CLARIANT GMBH (DE) 2005-02-09 EP disclosed
US-20040048749-A1 Microencapsulated biologically active substances that contain a water-soluble or water-dispersible comb polymer CLARIANT GMBH (DE) 2004-03-11 US disclosed
EP-1368387-A2 MICROENCAPSULATED BIOLOGICALLY ACTIVE SUBSTANCES THAT CONTAIN A WATER-SOLUBLE OR WATER-DISPERSIBLE COMB POLYMER Clariant GmbH (DE) 2003-12-10 EP disclosed
WO-2002062856-A2 MICROENCAPSULATED BIOLOGICALLY ACTIVE SUBSTANCES THAT CONTAIN A WATER-SOLUBLE OR WATER-DISPERSIBLE COMB POLYMER CLARIANT GMBH (DE) 2002-08-15 WO disclosed
JP-H0820726-A SILICONE RUBBER COMPOSITION SHIN ETSU CHEM CO LTD 1996-01-23 JP disclosed
US-4925822-A Disproportionation catalyst and process SHELL OIL COMPANY (US) 1990-05-15 US disclosed
EP-0236889-A2 Method of manufacture of fiber reinforced silicone elastomer DOW CORNING CORPORATION (US) 1987-09-16 EP disclosed
US-4640951-A MIXING POLYSILOXANE GUM, FIBER, AND SILICA FILLER; HEATING IN VACUUM DOW CORNING CORPORATION (US) 1987-02-03 US disclosed
US-4241120-A POLYVINYL CHLORIDE CONTAINING POLYMER GRAFTED ELECTROCONDUCTIVE CARBON RCA CORPORATION (US) 1980-12-23 US disclosed