Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Prenylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | MC4R | P32245 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prenylamine SCHEMBL77916 | 1.00 | HTR1A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL5053804 | 1.00 | HTR1A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL5525021 | 0.98 | HTR1A (0.97) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL29389965 | 0.98 | HTR1A (0.97) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL10614915 | 0.89 | CYP1A2 (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| SCHEMBL11206312 | 0.89 | ADRB2 (0.79) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL10616084 | 0.88 | HTR1A (0.78) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL11207869 | 0.88 | ADRB2 (0.77) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Bromide SCHEMBL11610736 | 0.88 | ADRB2 (0.77) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| SCHEMBL11212570 | 0.86 | KMT2A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1679 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3935111-B1 | CURABLE INK COMPOSITIONS | DOMINO PRINTING SCIENCES PLC (GB) | 2025-07-23 | — | — | EP | claimed |
| CN-118847375-A | Flotation reagent and method for carrying out flotation separation on micro-fine cassiterite and magnesium-containing gangue minerals | 中南大学 | 2024-10-29 | — | — | CN | claimed |
| CN-118768094-A | Desorption and recycling method of collector in flotation concentrate | 中南大学 | 2024-10-15 | — | — | CN | claimed |
| US-12071556-B2 | Curable ink composition | DOMINO PRINTING SCIENCES PLC (GB) | 2024-08-27 | — | — | US | claimed |
| CN-118491707-A | Flotation reagent and desorbent recycling method | 中南大学 | 2024-08-16 | — | — | CN | claimed |
| EP-4196123-B1 | TREATMENTS FOR INFECTIVE ENDOCARDITIS | DEVIE MEDICAL GMBH (DE) | 2024-08-14 | — | — | EP | claimed |
| CN-118106131-A | Composite flotation reagent for flotation of rutile in titanium tetrachloride inert waste residues and application | 龙佰四川矿冶有限公司 | 2024-05-31 | — | — | CN | claimed |
| EP-4305395-A1 | METHOD FOR FASTENING AN ASSEMBLY COMPRISING A STRAIN GAUGE | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2024-01-17 | — | — | EP | claimed |
| EP-3269717-B9 | POLYMORPHIC AND PSEUDOPOLYMORPHIC FORMS OF PHARMACEUTICAL COMPOUND NXL104 | PFIZER IRELAND PHARMACEUTICALS (IE) | 2023-08-09 | — | — | EP | claimed |
| EP-3269717-B2 | POLYMORPHIC AND PSEUDOPOLYMORPHIC FORMS OF PHARMACEUTICAL COMPOUND NXL104 | PFIZER IRELAND PHARMACEUTICALS (IE) | 2023-06-14 | — | — | EP | claimed |
| US-5288503-A | WATER-PERMEABLE DIFFUSION BARRIER OF POLYVINYL ALCOHOL | SRCHEM INCORPORATED (US) | 1994-02-22 | — | — | US | claimed |
| US-5260066-A | Cryogel bandage containing therapeutic agent | SRCHEM INCORPORATED (US) | 1993-11-09 | — | — | US | claimed |
| CN-1058132-A | Herbicidal combinations | ISHIHARA SANGYO KAISHA (JP) | 1992-01-29 | — | — | CN | claimed |
| CN-1012334-B | Fungicide and plant growth regulator | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1991-04-17 | — | — | CN | claimed |
| CN-1030003-A | bactericidal composition | SHELL AGRAR GMBH & CO KG (DE) | 1989-01-04 | — | — | CN | claimed |
| US-4782043-A | HYPOTENSIVES | MERCK & CO., INC. (US) | 1988-11-01 | — | — | US | claimed |
| CN-88102052-A | Bactericide composition | — | 1988-09-21 | — | — | CN | claimed |
| EP-0105872-B1 | NOVEL COSMETIC COMPOSITIONS CONTAINING PRENYLAMINE AND A PROCESS FOR THEIR PREPARATION | CAOLA KOZMETIKAI ES HAZTARTÄSVEGYIPARI VALLALAT (HU) | 1988-03-30 | — | — | EP | claimed |
| US-4618598-A | Method of regulating hormone function or release | DUKE UNIVERSITY (US) | 1986-10-21 | — | — | US | claimed |
| EP-0129189-A2 | Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same | MERCK & CO. INC. (US) | 1984-12-27 | — | — | EP | claimed |