Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Prenylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A known ✓ | Q14524 | 1/20 | 1.00 |
| ▸ | HTR1A | P08908 | 2/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 2/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | ADRA1A | P35348 | 2/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 2/20 | 1.00 |
| ▸ | DRD3 | P35462 | 2/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | ADRB2 | P07550 | 1/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | ADRA2B | P18089 | 1/20 | 1.00 |
| ▸ | ADRA2C | P18825 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | MC4R | P32245 | 1/20 | 1.00 |
| ▸ | HRH1 | P35367 | 1/20 | 1.00 |
| ▸ | SCN1A | P35498 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prenylamine SCHEMBL182253 | 1.00 | HTR1A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL77916 | 1.00 | HTR1A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL5525021 | 0.98 | HTR1A (0.97) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL29389965 | 0.98 | HTR1A (0.97) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL10614915 | 0.89 | CYP1A2 (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| SCHEMBL11206312 | 0.89 | ADRB2 (0.79) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Prenylamine SCHEMBL10616084 | 0.88 | HTR1A (0.78) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL11207869 | 0.88 | ADRB2 (0.77) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| Bromide SCHEMBL11610736 | 0.88 | ADRB2 (0.77) | HTR1AADORA3SLC6A2SLC6A4ADRA1A | |
| SCHEMBL11212570 | 0.86 | KMT2A (1.00) | HTR1AADORA3SLC6A2SLC6A4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931760-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | The University of Alabama (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044693-A2 | MULTI-FUNCTIONAL IONIC LIQUID COMPOSITIONS | THE UNIVERSITY OF ALABAMA (US) | 2007-04-19 | — | — | WO | disclosed |