Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1821813 | 0.80 | GABRA1 (0.41) | ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL28925989 | 0.78 | GABRA1 (0.40) | ALDH1A1ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL1819293 | 0.78 | GABRA1 (0.40) | ALDH1A1ALOX15TSHR | |
| SCHEMBL4602957 | 0.77 | — | — | |
| SCHEMBL21722446 | 0.73 | GABRA1 (0.30) | — | |
| Naphthoquinone SCHEMBL29639242 | 0.67 | DPP4 (0.44) | ALDH1A1ALOX15TSHR | |
| Naphthoquinone SCHEMBL1820512 | 0.67 | DPP4 (0.44) | ALDH1A1ALOX15TSHR | |
| SCHEMBL1772757 | 0.67 | CYP3A4 (0.34) | ALDH1A1ALOX15TSHR | |
| SCHEMBL31239234 | 0.65 | — | — | |
| SCHEMBL5485162 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737301-B2 | Preparation of 2-bicyclopropyl-2-yl-phenylamine through catalyzing the dehydrochlorination in the presence of a palladium complex; cost efficiency; used as intermediates for the preparation of fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-15 | — | — | US | claimed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | claimed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | claimed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | claimed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | claimed |
| EP-2560959-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-20 | — | — | EP | disclosed |
| EP-2560960-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-26 | — | — | EP | disclosed |
| US-8524915-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-8519151-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-27 | — | — | US | disclosed |
| US-8519152-B2 | Process for the preparation of pyrazole carboxylic acid amides | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-27 | — | — | US | disclosed |
| EP-2316813-B1 | Process for the preparation of amines | SYNGENTA PARTICIPATIONS AG (CH) | 2013-04-03 | — | — | EP | disclosed |
| EP-2560959-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLE CARBOXYLIC ACID AMIDES | Syngenta Participations AG (CH) | 2013-02-27 | — | — | EP | disclosed |
| EP-2316813-A1 | Process for the preparation of amines | Syngenta Participations AG (CH) | 2011-05-04 | — | — | EP | disclosed |
| US-7781615-B2 | Process for the preparation of amines | SYNGENTA CROP PROTECTION, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| US-7737301-B2 | Preparation of 2-bicyclopropyl-2-yl-phenylamine through catalyzing the dehydrochlorination in the presence of a palladium complex; cost efficiency; used as intermediates for the preparation of fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
| EP-1931618-B1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-08-05 | — | — | EP | disclosed |
| EP-1931618-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | Syngeta Participations AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007025693-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221855-A1 | PROCESS FOR THE PRODUCTION OF ANILINES | CBR3, C1S, C9 | ALDH1A1 183/4885ALOX15 3471/4885TSHR 910/4885 |
| US-20090221856-A1 | PROCESS FOR THE PREPARATION OF AMINES | HRH3, PAH, C1R | ALDH1A1 1504/4885ALOX15 2996/4885TSHR 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.