SCHEMBL18229239

SCHEMBL18229239

COC1=CC[CH]C(c2ccccc2)=C1OC

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 3/20 0.37
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MITF O75030 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CA4 P22748 1/20 0.32
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
PDE4A P27815 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6994658 0.77 AHR (0.38)
SCHEMBL5887269 0.70 LTA4H (0.46) MAPTALDH1A1HTTCA4MEN1
SCHEMBL5887527 0.69 ACHE (0.34) KMT2A
SCHEMBL5887387 0.68 LTA4H (0.51) MAPTALDH1A1HTTNPSR1CA4
SCHEMBL4007569 0.68 ACHE (0.33) KMT2A
Biphenyl SCHEMBL28881047 0.59 ALDH1A1 (0.69) PDE4BMAPTALDH1A1CA4MEN1
Biphenyl SCHEMBL3908169 0.59 ALDH1A1 (0.69) PDE4BMAPTALDH1A1CA4MEN1
SCHEMBL5907503 0.57
Biphenyl SCHEMBL18139126 0.57 ALDH1A1 (0.64) PDE4BMAPTALDH1A1CA4MEN1
Biphenyl SCHEMBL9139034 0.57 ALDH1A1 (0.64) PDE4BMAPTALDH1A1CA4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3294783-A1 HIGH PERFORMANCE (METH)ACRYLATE ADHESIVE COMPOSITION 3M Innovative Properties Company (US) 2018-03-21 EP disclosed
WO-2016182773-A1 HIGH PERFORMANCE (METH)ACRYLATE ADHESIVE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY (US) 2016-11-17 WO disclosed