Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197897 | 0.85 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1IDO1KDM4ENPC1 | |
| SCHEMBL6165261 | 0.83 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1IDO1KDM4ENPC1 | |
| SCHEMBL29637140 | 0.77 | MMP2 (0.34) | ALDH1A1L3MBTL1IDO1 | |
| SCHEMBL20849 | 0.76 | GAA (0.47) | ALDH1A1IDO1KDM4ENPC1GAA | |
| SCHEMBL5612902 | 0.76 | AKT1 (0.41) | ALDH1A1NPC1HSD17B10DCUN1D1SMN1; SMN2 | |
| SCHEMBL5612891 | 0.76 | PBRM1 (0.47) | ALDH1A1IDO1KDM4ENPC1GAA | |
| SCHEMBL6252050 | 0.76 | IDO1 (0.39) | ALDH1A1L3MBTL1IDO1KDM4ENPC1 | |
| SCHEMBL11246560 | 0.76 | GAA (0.47) | ALDH1A1IDO1KDM4ENPC1GAA | |
| SCHEMBL8781512 | 0.76 | F2 (0.33) | ALDH1A1L3MBTL1MEN1KMT2AKCNN4 | |
| SCHEMBL207829 | 0.76 | IDO1 (0.47) | ALDH1A1IDO1KDM4EHSD17B10DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021016670-A1 | ANTIVIRAL AGENTS AND USES THEREOF | GRIFFITH UNIVERSITY (AU) | 2021-02-04 | — | — | WO | disclosed |
| EP-1981876-B1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LTD (GB) | 2011-05-04 | — | — | EP | disclosed |
| US-20100158863-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2010-06-24 | — | — | US | disclosed |
| EP-1981876-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | Arrow Therapeutics Limited (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007080401-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2007-07-19 | — | — | WO | disclosed |
| US-6451820-B1 | Substituted 1-(4-aminophenly)triazoles and their use as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-09-17 | — | — | US | disclosed |
| WO-2001072740-A1 | SUBSTITUTED 1-(4-AMINOPHENYL) TRIAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| CN-1053660-C | Process for preparing indole derivatives containing 1,2,4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 2000-06-21 | — | — | CN | disclosed |
| CN-1037843-C | Process for preparing indole derivatives containing 1,2, 4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 1998-03-25 | — | — | CN | disclosed |
| US-5717104-A | Process for preparing indole derivatives containing a 1,2,4-triazol-1-yl substituent | MERCK, SHARP & DOHME, LTD. (GB) | 1998-02-10 | — | — | US | disclosed |
| CN-1166486-A | Process for preparing indole derivatives containing 1,2,4-triazol-1-yl substituents | MERCK SHARP & DOHME (GB) | 1997-12-03 | — | — | CN | disclosed |
| EP-0651748-B1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT | MERCK SHARP & DOHME (GB) | 1997-10-08 | — | — | EP | disclosed |
| US-5567819-A | Process for preparing indole derivatives containing a 1,2,4-triazol-1-yl substituent | MERCK, SHARP & DOHME, LTD. (GB) | 1996-10-22 | — | — | US | disclosed |
| EP-0651748-A1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT. | MERCK SHARP & DOHME (GB) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002476-A1 | PROCESS FOR PREPARING INDOLE DERIVATIVES CONTAINING A 1,2,4-TRIAZOL-1-YL SUBSTITUENT | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
| EP-0040357-B1 | PROCESS FOR THE PREPARATION OF V-TRIAZOLYL-(2) PHENOLS | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0040357-A1 | Process for the preparation of v-triazolyl-(2) phenols | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158863-A1 | TRIAZOLOANILINOPYRIMIDINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | SLC28A1, TPMT, ACE | ALDH1A1 443/4885L3MBTL1 4037/4885IDO1 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.