Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980575 | 0.87 | ALDH1A1 (0.54) | SORT1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL1822050 | 0.85 | MRGPRX4 (0.46) | SORT1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL4455829 | 0.82 | P2RX1 (0.46) | SORT1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL13142979 | 0.82 | MRGPRX4 (0.52) | SORT1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL2677449 | 0.81 | ESRRG (0.44) | SORT1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL10524850 | 0.80 | ALDH1A1 (0.61) | P2RX1TMPRSS4P2RX4P2RX7ALDH1A1 | |
| SCHEMBL115659 | 0.76 | ALDH1A1 (0.65) | SORT1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1821214 | 0.75 | ALOX12 (0.53) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1821212 | 0.75 | ALOX12 (0.53) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27866247 | 0.74 | ALDH1A1 (0.62) | SORT1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813486-B1 | Fatty acid acetylated salicylates and their uses | CATABASIS PHARMACEUTICALS INC (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-2315740-B1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS INC (US) | 2017-10-25 | — | — | EP | disclosed |
| EP-2813486-A1 | Fatty acid acetylated salicylates and their uses | Catabasis Pharmaceuticals, Inc. (US) | 2014-12-17 | — | — | EP | disclosed |
| EP-2315740-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | Catabasis Pharmaceuticals, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| WO-2010006085-A1 | FATTY ACID ACETYLATED SALICYLATES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2010-01-14 | — | — | WO | disclosed |