Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 4/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13752999 | 0.84 | PPARD (0.50) | ESRRGKDM4EHTT | |
| SCHEMBL13753082 | 0.84 | CES2 (0.60) | SORT1ALDH1A1POLBCFTRMRGPRX4 | |
| SCHEMBL8980575 | 0.83 | ALDH1A1 (0.54) | P2RX1TMPRSS4P2RX4P2RX7SORT1 | |
| SCHEMBL10524850 | 0.82 | ALDH1A1 (0.61) | P2RX1TMPRSS4P2RX4P2RX7ALDH1A1 | |
| SCHEMBL1822050 | 0.82 | MRGPRX4 (0.46) | P2RX1TMPRSS4P2RX4P2RX7SORT1 | |
| SCHEMBL1822980 | 0.82 | SORT1 (0.46) | P2RX1TMPRSS4P2RX4P2RX7SORT1 | |
| SCHEMBL13753003 | 0.81 | DDR1 (0.58) | TMPRSS4SORT1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL13753088 | 0.81 | CES2 (0.60) | TMPRSS4SORT1ALDH1A1POLBMRGPRX4 | |
| SCHEMBL13753890 | 0.80 | JAK2 (0.57) | P2RX7MEN1KMT2AMRGPRX4CRHR2 | |
| SCHEMBL13754025 | 0.80 | CCR2 (0.52) | ALDH1A1CFTRKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045083-A2 | COMBINATION THERAPY FOR NEUROPROTECTION | S.H. PHARMA., LTD (KR) | 2009-04-09 | — | — | WO | claimed |