Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.60 |
| ▸ | SCD | O00767 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230427 | 0.91 | ADORA1 (0.54) | ADORA3ADORA1ADORA2ATRPV4 | |
| SCHEMBL18230402 | 0.90 | ADORA1 (0.55) | ADORA3ADORA1ADORA2ANPC1RAB9A | |
| SCHEMBL18230382 | 0.89 | TRPV1 (0.53) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL18230521 | 0.88 | TRPV1 (0.59) | ADORA3ADORA1ADORA2ANPC1RAB9A | |
| SCHEMBL18230398 | 0.87 | TRPV1 (0.56) | ADORA3ADORA1ADORA2ANPC1RAB9A | |
| SCHEMBL18230372 | 0.84 | TRPV1 (0.55) | ADORA3ADORA1ADORA2AMEN1KMT2A | |
| SCHEMBL18230222 | 0.82 | ADORA2A (0.48) | ADORA3ADORA1ADORA2ASCDNPC1 | |
| SCHEMBL18230411 | 0.82 | ADORA3 (0.61) | ADORA3ADORA1ADORA2ASCDNPC1 | |
| SCHEMBL18230491 | 0.82 | GRM1 (0.47) | ADORA3ADORA1ADORA2ANPC1RAB9A | |
| SCHEMBL18230228 | 0.82 | GCK (0.52) | ADORA3ADORA1ADORA2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |