Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM4B | O94953 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230382 | 0.95 | TRPV1 (0.53) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230228 | 0.92 | GCK (0.52) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230427 | 0.91 | ADORA1 (0.54) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230222 | 0.90 | ADORA2A (0.48) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230261 | 0.90 | ADORA3 (0.62) | ADORA1ADORA2AADORA3NPC1RAB9A | |
| SCHEMBL18230312 | 0.88 | GCK (0.55) | ADORA1ADORA2AADORA3NPC1RAB9A | |
| SCHEMBL18230521 | 0.88 | TRPV1 (0.59) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230491 | 0.86 | GRM1 (0.47) | ADORA1ADORA2AADORA3NPC1RAB9A | |
| SCHEMBL18230398 | 0.85 | TRPV1 (0.56) | ADORA1ADORA2AADORA3KDM4AKDM4B | |
| SCHEMBL18230522 | 0.84 | PCSK9 (0.50) | ADORA1ADORA2AADORA3KDM4AKDM4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |