Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18230488 | 0.81 | ADORA2A (0.46) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18230482 | 0.79 | CASP3 (0.56) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18230342 | 0.78 | ADORA2A (0.44) | KDM4EKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL19638116 | 0.78 | ADORA2A (0.54) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18230414 | 0.78 | ADORA2A (0.51) | KDM4ESMN1; SMN2MAPTALDH1A1L3MBTL1 | |
| SCHEMBL18230233 | 0.77 | ADORA2A (0.48) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18230254 | 0.77 | TRPV4 (0.52) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18230294 | 0.77 | TRPV1 (0.54) | KDM4EKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL18236379 | 0.77 | ADORA2A (0.50) | KDM4EKMT2AMEN1POLBRAB9A | |
| SCHEMBL18230439 | 0.77 | LMNA (0.53) | KDM4EKMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183173-A1 | ANTIPARASITIC COMPOUNDS | Avista Pharma Solutions (US) | 2016-11-17 | — | — | WO | disclosed |